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Trans-4-Amino Cyclohexanol (4-TAC) (CAS NO : 27489-62-9)

Trans-4-Aminocyclohexanol (4-TAC) is a bicyclic amino alcohol used in synthesizing chiral intermediates for APIs in pharmaceutical industry. For targeting neuroactive agents and selective ligands, the 4-TAC intermediate is currently in drug discovery programs . The trans configuration of 4-TAC gives stereochemical stability for enantioselective synthesis essentials. 4-TAC currently evaluated cyclohexanol for its potential in targeting central nervous system (CNS), analgesic, and anti-inflammatory pathways.

Trans-4-Amino Cyclohexanol (4-TAC)
Trans-4-Amino Cyclohexanol (4-TAC)

Trans-4-Aminocyclohexanol (4-TAC) is a bicyclic amino alcohol used in synthesizing chiral intermediates for APIs in pharmaceutical industry. For targeting neuroactive agents and selective ligands, the 4-TAC intermediate is currently in drug discovery programs . The trans configuration of 4-TAC gives stereochemical stability for enantioselective synthesis essentials. 4-TAC currently evaluated cyclohexanol for its potential in targeting central nervous system (CNS), analgesic, and anti-inflammatory pathways.

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Pharmaceutical

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Pharmaceutical Actives & Precursors

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Intermediates & Precursors

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Chemical Properties & Specifications

Applications of Trans-4-Amino Cyclohexanol (4-TAC)

Pharmaceutical Intermediate

Used in the synthesis of chiral drug molecules, particularly CNS modulators

Medicinal Chemistry

Scaffold in the design of selective ligands or inhibitors

R&D

Utilized in stereoselective synthesis studies

Additional Feature

*Readily available for functionalization and derivatization *Suitable for formulation into custom drug discovery programs

Specified End Use

Precursor in the development of neuropharmaceuticals, pain modulators, and specialized CNS drugs

Have Questions About Trans-4-Amino Cyclohexanol (4-TAC)?
We've Got Answers.

Assay ≥98%, validated by HPLC methods.

Yes, often used in regulatory filing pathways as an intermediate.

Enantiomerically pure variants can be offered upon request.

Yes, COA, MSDS, and export documents are provided. REACH status available.

Dispatch in 7–10 days. MOQ typically starts from 1 kg for R&D.

As a stable scaffold in asymmetric synthesis or CNS-focused lead molecules.

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