Unlock the potential of cyanation for APIs, agrochemicals, and beyond with state‑of‑the‑art manufacturing facilities and an in‑house R&D team.
Cyanation is a chemical process that introduces a cyano group (-CN) into a molecule, typically forming nitriles. It involves substituting a functional group (commonly halides, aryl halides, or alkyl halides) with a cyanide ion, usually sourced from inorganic or organic cyanides like KCN, NaCN, or trimethylsilyl cyanide (TMSCN).
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CAS No. : 84057-84-1
Category : Pharmaceutical Actives & Precursors
Sub-Category : Active Pharmaceutical Ingredients (APIs)
CAS No. : 148553-50-8
Category : Pharmaceutical Actives & Precursors
Sub-Category : Active Pharmaceutical Ingredients (APIs)
CAS No. : 500-22-1
Category : Crop Protection & Pest Control
Sub-Category : Intermediates & Precursors
Essential in synthesizing nitrile‑containing APIs used in cardiovascular treatments, antifungal agents, and cancer therapies.
Key to producing intermediates in herbicides, fungicides, and insecticides required for improving crop yield.
Used in producing solvents, plasticizers, corrosion inhibitors, and synthetic rubbers for diverse applications.
Cyanation plays a critical role in the multi-step synthesis of Remdesivir, an antiviral drug used to treat RNA virus infections, including COVID-19. The key cyanation step occurs during the formation of the C-nucleoside scaffold, where a ribose-derived sugar intermediate undergoes cyanation at the C1’ position.
Reagent: Trimethylsilyl cyanide (TMSCN)
Solvent: Anhydrous dichloromethane (CH₂Cl₂)
Catalyst: Boron trifluoride etherate (BF₃·Et₂O)
Cyanation is a chemical process that introduces a cyano group (-CN) in...
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From lab-scale testing to pilot-scale production to finished formulations and regulatory support, our CRO services are designed to streamline your journey to market with precision and expertise.
Our CMO services enable seamless production processes to meet your custom specifications and timelines, catering to both small-scale and large-scale production needs.
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A double-stage scrubbing setup ensures safe and efficient reatment of vent gases, minimizing emissions.
Equipped with sensors and emergency quenching mechanisms for precise control and enhanced safety.
Dedicated segregation and treatment facilities handle all waste streams from cyanation reactions with care.
👥 Speaker: Vilas Sahasrabuddhey
👤 Host: Hersh Manek - Business Head, Flavors & Fragrances, Scimplify
👤 Co-Host: Nikita Ghode - Senior Manager, Market Intelligence, Scimplify
👥 Speaker: Dr. T Pavan Kumar
👤 Host: Mr Karthik Kumar - Business Head, Pharmaceuticals, Scimplify
