Pregabalin is an anticonvulsant therapeutic medication primarily used to treat neuropathic pain, fibromyalgia, seizures, and generalized anxiety disorder. It functions by binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system, inhibiting excitatory neurotransmitter release. Pregabalin is widely prescribed for its effectiveness in reducing pain, controlling seizures, and alleviating anxiety. This Api has IP/ USP/ Ph. Eur/ BP/ KP grades.
Pregabalin is an anticonvulsant therapeutic medication primarily used to treat neuropathic pain, fibromyalgia, seizures, and generalized anxiety disorder. It functions by binding to the alpha2-delta subunit of voltage-gated calcium channels in the central nervous system, inhibiting excitatory neurotransmitter release. Pregabalin is widely prescribed for its effectiveness in reducing pain, controlling seizures, and alleviating anxiety. This Api has IP/ USP/ Ph. Eur/ BP/ KP grades.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray. P264: Wash hands thoroughly after handling. P270: Do not eat, drink, or smoke when using this product. P280: Wear protective gloves/eye protection/face protection. P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing.
Limited information regarding overdose with pregabalin. The highest known accidental overdose of pregabalin during clinical development was 8000 mg; this event was without significant clinical consequences. The most commonly reported adverse events with overdose were reduced consciousness, confusional state, agitation, depression/anxiety, and restlessness in the postmarketing studies. In addition, heart block, seizures, and death have also been reported in some patients taking combination with other CNS depressants.
Pregabalin can be removed by standard hemodialysis procedures, resulting in approximately 50% clearance of pregabalin in 4 hours.
Pregabalin is commonly used to treat pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, and spinal cord injury.
It is used as an adjunct therapy for partial-onset seizures and generalized anxiety disorder, enhancing overall seizure control.
Pregabalin provides relief from fibromyalgia-related pain, stiffness, and sleep disturbances.
Store at 25 °C (77 °F); excursions permitted to 15 to 30 °C (59 to 86 °F). Maintain it in cool, dry, well-ventilated area, away from moisture and incompatible substances.
Available in various sizes, including 25 kg double poly bags within HDPE drums for bulk applications.
2 years
