

P-Nitrobenzoyl Chloride (CAS 122-04-3) is a critical building block in the API intermediates market, primarily utilized for the synthesis of complex nitro-substituted aromatic compounds and radiopharmaceuticals for neuroimaging where high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) are essential to ensure reaction efficiency. 4-Nitrobenzoyl chloride serves as a high-performance precursor in the current shift toward strategic global sourcing, as CDMOs increasingly require custom synthesis services that provide rigorous impurity profiling and analytical validation to meet stringent regulatory and environmental standards. 4-Nitrobenzoic acid chloride remains a preferred choice for advanced process development and bulk chemical supplier procurement, reflecting a growing industry demand for reliable precursors that optimize yields in large-scale commercial manufacturing of dyes and specialty polymers while maintaining precise crystalline morphology for downstream stability (Pharma/API purity 99% | General Industry purity 98%). We are an established global intermediates supplier with >= 99% purity, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting P-Nitrobenzoyl Chloride COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities

P-Nitrobenzoyl Chloride (CAS 122-04-3) is a critical building block in the API intermediates market, primarily utilized for the synthesis of complex nitro-substituted aromatic compounds and radiopharmaceuticals for neuroimaging where high purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) are essential to ensure reaction efficiency. 4-Nitrobenzoyl chloride serves as a high-performance precursor in the current shift toward strategic global sourcing, as CDMOs increasingly require custom synthesis services that provide rigorous impurity profiling and analytical validation to meet stringent regulatory and environmental standards. 4-Nitrobenzoic acid chloride remains a pr...

Chemical Properties & Specifications
P234, P260, P280, P303+P361+P353, P304+P340+P310, and P305+P351+P338
Skin Corr. 1B (100%)
Met. Corr. 1 (96.3%)
An important building block utilized as a precursor in the synthesis of various medicinal compounds, active pharmaceutical ingredients, and essential drugs like folic acid and procaine hydrochloride
A versatile acylating agent employed in Michael additions, Henry reactions, O-alkylation, and cycloaddition reactions to introduce nitrobenzoyl groups into complex organic molecules
A specialized reagent used for the derivatization of hydroxy and amino groups to improve UV detection and quantification of compounds such as polyhydric alcohols and digitalis glycosides during high-performance liquid chromatography
A critical starting material used in the production of specialized dyes, organic pigments, and color developers for the textile and information industries.
P-Nitrobenzoyl Chloride, also known as 4-nitrobenzoyl chloride, is a highly reactive acylating agent and organic compound used as a precursor in the synthesis of 4-aminobenzoic acid, benzofurans, and various nitro-substituted aromatic compounds
This compound is widely used in the pharmaceutical, agrochemical, dye, and polymer industries for the production of active pharmaceutical ingredients, specialty colorants, and high-performance materials
It is soluble in tetrahydrofuran, dichloromethane, chloroform, and pyridine, but it is moisture-sensitive and decomposes in water or alcohols
Standard specifications include CAS number 122-04-3, minimum purity of 98% (by GC or titration), and documentation such as COA, TDS, SDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
Description : P-Nitrobenzoyl Chloride (CAS 122-04-3) is a critical building block in the API intermediates market,...