Enabling the production of high-value chemicals like pharmaceuticals, agrochemicals, and more with precise and efficient synthesis of complex molecules.
Biocatalysis harnesses the power of enzymes or microorganisms to catalyze chemical reactions, enabling the efficient and sustainable synthesis of complex molecules. This green chemistry approach is crucial for producing high-value compounds in pharmaceuticals, agrochemicals, and specialty materials.
Enables the synthesis of chiral drugs, antibiotics, and APIs with unmatched precision and efficiency.
Used for producing bio-based pesticides, herbicides, and fertilizers with eco-friendly processes.
Facilitates the creation of bio-based polymers, surfactants, and fine chemicals for diverse applications.
Sitagliptin, a DPP-4 inhibitor used in the treatment of type 2 diabetes, is synthesized using a highly efficient biocatalytic fermentation process. This approach utilizes enzymatic transformation to produce the key chiral intermediate, reducing the need for traditional chemical resolution methods.
Substrate: A prochiral ketone intermediate
Enzyme: Transaminase (TA) - a biocatalyst that enables asymmetric amination
Cofactor Regeneration: Pyridoxal phosphate (PLP)
Cyanation is a chemical process that introduces a cyano group (-CN) in...
Hydrogenation is a chemical process in which hydrogen (H2) is added to...
Biocatalysis harnesses the power of enzymes or microorganisms to catal...
Fluorination is a chemical process used to introduce one or more fluor...
From preclinical testing to formulation and regulatory support, our CRO services are designed to streamline your path to market with precision and expertise.
Enabling seamless production processes to meet your specifications and timelines with our CMO services, catering to both small-scale and large-scale production needs.
Optimal temperature and pH control for the most effective working of the used enzymes.
Stainless steel and glass-lined reactors prevent the deactivation of the enzymes.
Specialized bioreactors and strict environmental management to maximize yield and sustainability.
👥 Speaker: Vilas Sahasrabuddhey
👤 Host: Hersh Manek - Business Head, Flavors & Fragrances, Scimplify
👤 Co-Host: Nikita Ghode - Senior Manager, Market Intelligence, Scimplify
👥 Speaker: Dr. T Pavan Kumar
👤 Host: Mr Karthik Kumar - Business Head, Pharmaceuticals, Scimplify