Empowering pharmaceuticals, agrochemicals, and industrial chemicals with precision fluorination techniques
Fluorination is a chemical process used to introduce one or more fluorine atoms into a molecule. This reaction is essential in modern synthetic chemistry due to fluorine's unique properties, such as high electronegativity, small atomic size, and ability to improve the stability, bioactivity, and lipophilicity of compounds.
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Increases drug efficacy and bioavailability, making synthesizing APIs in anti-inflammatory, antiviral, and anticancer therapies essential.
Compounds made via fluorination enhance the stability and efficiency of herbicides, insecticides, and fungicides for better crop protection.
Helps develop materials with high thermal stability and dielectric properties, including semiconductors and battery components.
Fluorination is a key step in the synthesis of Apalutamide, a non-steroidal antiandrogen (NSAA) used for treating prostate cancer. The selective incorporation of fluorine (-F) and trifluoromethyl (-CF₃) groups enhances metabolic stability, bioavailability, and androgen receptor binding affinity.
Fluorinated Intermediate: 2-Fluoro-5-nitro benzonitrile
Fluorination Method: Electrophilic fluorination with Selectfluor, nucleophilic fluorination using HF-based reagents, or direct trifluoromethylation
Cyanation is a chemical process that introduces a cyano group (-CN) in...
Hydrogenation is a chemical process in which hydrogen (H2) is added to...
Biocatalysis harnesses the power of enzymes or microorganisms to catal...
Fluorination is a chemical process used to introduce one or more fluor...
From preclinical testing to formulation and regulatory support, our CRO services are designed to streamline your path to market with precision and expertise.
Enabling seamless production processes to meet your specifications and timelines with our CMO services, catering to both small-scale and large-scale production needs.
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Specialized Hastealloy reactor for precise and efficient fluorination processes.
Cryo reactors perform controlled fluorination at sub-zero temperatures
Separate Effluent treatment facility to isolate Fluorine waste streams.
Systems to handle Aq. HF of up to 70% concentration.
👥 Speaker: Vilas Sahasrabuddhey
👤 Host: Hersh Manek - Business Head, Flavors & Fragrances, Scimplify
👤 Co-Host: Nikita Ghode - Senior Manager, Market Intelligence, Scimplify
👥 Speaker: Dr. T Pavan Kumar
👤 Host: Mr Karthik Kumar - Business Head, Pharmaceuticals, Scimplify
