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Levocetirizine (CAS 130018-77-8) serves as a critical component in the global API intermediates market, primarily utilized for the production of high-efficacy antihistamines targeting allergic rhinitis and chronic urticaria. As a leading bulk chemical supplier, we recognize that CDMOs are increasingly demanding high-purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) to ensure the enantiomeric precision of the (R)-enantiomer, which is vital for maintaining superior clinical profiles and meeting stringent international pharmacopeial standards. Levocetirizine dihydrochloride (CAS 130018-87-0) has experienced a significant increase in demand due to strategic global sourcing shifts, with manufacturers actively seeking custom synthesis services that offer rigorous analytical validation and fully traceable supply chains to navigate the complexities of evolving regulatory landscapes. This movement reflects a broader industry trend toward securing high-quality precursors that can withstand intensive audit processes while optimizing cost-efficiency in large-scale commercial production. Levocetirizine free base (CAS 130018-77-8) continues to be a preferred choice in advanced formulation development, where managing specific polymorphic forms is essential for achieving bioequivalence and stability. To address these technical requirements, suppliers are implementing advanced crystallization techniques and sustainable green chemistry protocols to provide consistent batches (Pharma/API purity 99% | General Industry purity 98%), aligning with global sustainability initiatives and the growing necessity for high-performance chemical building blocks that guarantee therapeutic safety. We are an established global API supplier offering >= 99% purity for semi-finished formulators, providing comprehensive analytical testing (HPLC/NMR/MS) and supporting Levocetirizine with COA, TDS, and SDS documentation alongside region-specific regulatory support, reliable lead times, and worldwide supply chain capabilities.
Levocetirizine (CAS 130018-77-8) serves as a critical component in the global API intermediates market, primarily utilized for the production of high-efficacy antihistamines targeting allergic rhinitis and chronic urticaria. As a leading bulk chemical supplier, we recognize that CDMOs are increasingly demanding high-purity fine chemicals (Pharma/API purity 99% | General Industry purity 98%) to ensure the enantiomeric precision of the (R)-enantiomer, which is vital for maintaining superior clinical profiles and meeting stringent international pharmacopeial standards. Levocetirizine dihydrochloride (CAS 130018-87-0) has experienced a significant increase in demand due to strategic global sourc...
Chemical Properties & Specifications
P264, P270, P273, P301+P312, P330, P391, and P501
Acute Tox. 4 (98.2%)
Aquatic Acute 1 (88.3%)
A potent and selective H1-receptor antagonist used for the symptomatic relief of allergic rhinitis, including seasonal and perennial variants, and the treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
An R-enantiomer of cetirizine dihydrochloride utilized in the formulation of oral tablets and solutions to inhibit histamine-induced effects such as sneezing, rhinorrhea, and pruritus
A therapeutic compound that modulates the allergic response by inhibiting the release of pro-inflammatory cytokines, eicosanoids, and limiting eosinophil recruitment at clinically relevant concentrations.
LEVOCETIRIZINE is a second or third-generation antihistamine used for the symptomatic relief of allergic rhinitis, hay fever, and chronic idiopathic urticaria by blocking the action of histamine in the body
It is primarily used in the pharmaceutical industry for the production of allergy medications and respiratory treatments
This ingredient is compatible with oral tablets, oral solutions, fast-dissolving films, and orally disintegrating tablets
Standard specifications include CAS number 130018-87-0, high purity (typically ≥98%), and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Active Pharmaceutical Ingredients (APIs)
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