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Chloroform is a clear, volatile, and dense liquid used extensively as a non-flammable solvent. It is a chlorinated hydrocarbon with excellent solvating power for organic molecules and polymers. Once used as an anesthetic, it is now primarily found in laboratory, pharmaceutical, and industrial applications such as DNA/RNA extraction, dye manufacturing, and chemical synthesis.
Chloroform is a clear, volatile, and dense liquid used extensively as a non-flammable solvent. It is a chlorinated hydrocarbon with excellent solvating power for organic molecules and polymers. Once used as an anesthetic, it is now primarily found in laboratory, pharmaceutical, and industrial applications such as DNA/RNA extraction, dye manufacturing, and chemical synthesis.
Chemical Properties & Specifications
Category 4: Acute oral toxicity Category 3: Acute Inhalation Toxicity - Vapors Category 2: Skin Corrosion/Irritation Category 2: Serious Eye Damage/Eye Irritation Carcinogenicity Category 2: Reproductive Toxicity Category 2: Specific target organ toxicity (single exposure) Target Organs - Central nervous system (CNS) Category 3: Specific target organ toxicity - (repeated exposure) Category 2: Target Organs - Liver, Kidney.
Used as a reaction medium in active pharmaceutical ingredient (API) synthesis.
Crucial component in phenol:chloroform extraction for isolating DNA/RNA.
Solvent for cellulose esters, fats, alkaloids, and rubber processing.
Used for intermediate purification and solvating colorant molecules.
*Available in bulk for formulation plants, R&D institutions, and chemical reactors *Suitable for both analytical and preparative chromatography processes *Common grades include stabilized (with ethanol) and unstabilized chloroform
15–30°C (59–86°F), away from light
Store in amber glass/HDPE drums with stabilizers
2.5 L, 5 L, 25 L, and 250 L barrels (with ethanol stabilizer if applicable)
2 drums high (palletized)
UN 1888 | Class 6.1 | PG III | Toxic liquid, organic, n.o.s.
As a solvent in polymer chemistry, pigment processing, and pharmaceutical synthesis.
It’s used in molecular biology for RNA/DNA purification in phenol:chloroform extraction.
No. It’s banned as an anesthetic due to toxicity. It is for external, industrial use only.
REACH/TSCA-listed; typically ISO 9001, with stabilizer tracking in COAs.
Yes. Stabilized with ethanol (0.75–1%) is standard. Unstabilized available on request.
Yes, classified as toxic organic liquid (UN 1888), requires proper handling and labeling.
Yes. Bulk supply and scheduled dispatch agreements impact pricing and lead time.
Includes purification columns, photo-stabilization controls, bulk distillation units, and in-line GC verification.
Ranges from 500 to 5000 MT/year depending on facility size and grade diversity.
Group 2B carcinogen – handle with caution status.
Trichloromethane, Methyl trichloride, Methane trichloride.
