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Chloroform

Chloroform

CAS Number: 67-66-3

Molecular Formula: CHCl3

Solvent–Polar Aprotic HalogenatedNon-polar organic solvateInhibit photodecompositionEthanol stabilizerNon-flammableAlternative to diethyl etherResidue-freeREACH, TSCA, EPA Compliant

About Chloroform

Chloroform is a clear, volatile, and dense liquid used extensively as a non-flammable solvent. It is a chlorinated hydrocarbon with excellent solvating power for organic molecules and polymers. Once used as an anesthetic, it is now primarily found in laboratory, pharmaceutical, and industrial applications such as DNA/R...

Chloroform Specifications

CAS Number
67-66-3
Molecular Formula
CHCl3
IUPAC Name
Trichloromethane
Canonical SMILES
ClC(Cl)Cl
InChI Key
HEDRZPFGACZZDS-UHFFFAOYSA-N
InChI
1S/CHCl3/c2-1(3)4/h1H
PubChem CID
6212
EINECS Number
200-663-8
MDL Number
MFCD00000847
UNSPSC Code
12142211
eClass
34030101
NACRES
NA.22
HSN No
29031300
Appearance
Clear, colorless liquid
Odor
Sweet, characteristic odor
Boiling Point
61.2°C
Melting Point
-63.5°C
Density
1.48 g/mL at 20°C
Refractive Index
1.445–1.448
Vapor Pressure
160 mmHg @ 20°C
Solubility
Slightly in water; miscible with ethanol, ether, benzene
Hazard identification
Category 4: Acute oral toxicity Category 3: Acute Inhalation Toxicity - Vapors Category 2: Skin Corrosion/Irritation Category 2: Serious Eye Damage/Eye Irritation Carcinogenicity Category 2: Reproductive Toxicity Category 2: Specific target organ toxicity (single exposure) Target Organs - Central nervous system (CNS) Category 3: Specific target organ toxicity - (repeated exposure) Category 2: Target Organs - Liver, Kidney.

Pharmaceutical Industry

Used as a reaction medium in active pharmaceutical ingredient (API) synthesis.

Molecular Biology

Crucial component in phenol:chloroform extraction for isolating DNA/RNA.

Polymer and Resin Manufacturing

Solvent for cellulose esters, fats, alkaloids, and rubber processing.

Dye and Pigment Industry

Used for intermediate purification and solvating colorant molecules.

Direct End user

*Available in bulk for formulation plants, R&D institutions, and chemical reactors *Suitable for both analytical and preparative chromatography processes *Common grades include stabilized (with ethanol) and unstabilized chloroform

Storage Temp

15–30°C (59–86°F), away from light

Protection

Store in amber glass/HDPE drums with stabilizers

Packaging

2.5 L, 5 L, 25 L, and 250 L barrels (with ethanol stabilizer if applicable)

Stacking

2 drums high (palletized)

Transport

UN 1888 | Class 6.1 | PG III | Toxic liquid, organic, n.o.s.

MSDS
Download

Chloroform FAQs

Minimum Order Quantity

25 kg (pilot) · 1 MT (commercial)

Lead Time

3 – 5 weeks ex-works

Incoterms

FOB · CIF

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

Regional Availability

India · EU · Middle East · Southeast Asia

Documentation

SDS · COA · TDS available on request

Compliance & Quality

REACH registered*

GHS/SDS available

ISO 9001:2015 site*

RoHS compliant*

Global sourcing network

Consistent quality & reliability

End-to-end technical support

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