1-(6-Methyl-3-pyridinyl)-2-(4-methylsulfonyl)phenyl ethanone, commonly known as Keto Sulfone, is a synthetic intermediate and impurity associated with the production of Etoricoxib, a selective COX-2 inhibitor. It is used in pharmaceutical quality control to ensure drug purity and compliance with regulatory standards.
1-(6-Methyl-3-pyridinyl)-2-(4-methylsulfonyl)phenyl ethanone, commonly known as Keto Sulfone, is a synthetic intermediate and impurity associated with the production of Etoricoxib, a selective COX-2 inhibitor. It is used in pharmaceutical quality control to ensure drug purity and compliance with regulatory standards.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
Used as an impurity reference standard in the manufacturing and quality control of Etoricoxib API and finished formulations.
Employed in the validation of HPLC and other analytical methods for impurity profiling.
Used in drug discovery and impurity profiling studies related to COX-2 inhibitors and anti-inflammatory compounds.
It is used as an impurity reference standard for the quality control of Etoricoxib, ensuring compliance with pharmacopeial standards and regulatory requirements.
It allows pharmaceutical companies to identify and quantify impurities, ensuring the purity, safety, and efficacy of Etoricoxib drug products during manufacturing and stability testing.
High-performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry (LC-MS), and gas chromatography-mass spectrometry (GC-MS) are commonly used for the detection and quantification of this impurity.
Yes, it is stable when stored in a cool, dry place away from light and moisture. Proper storage ensures long-term stability for accurate analytical testing.
CAS No. : 141109-14-0
Category : Intermediate
CAS No. : 148553-50-8
Category : Pharmaceutical Actives & Precursors
Sub-Category : Active Pharmaceutical Ingredients (APIs)
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