Search through
Venlafaxine Hydrochloride is a synthetic antidepressant belonging to the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Also known as VENLAFAXINE HCl by manufacturers and fundamentally used to treat major depressive disorder, generalized anxiety disorder and panic disorder. Venlafaxine is a racemic mixture of two enantiomers structurally, each contributing to its pharmacological activity. The Venlafaxine compound is well-absorbed orally and extensively metabolized in the liver, with its active metabolite, O-desmethylvenlafaxine (ODV), also contributing to its therapeutic effects. Venlafaxine supplier employee it in the production of oral dosage forms such as tablets and extended-release capsules, Venlafaxine Hydrochloride serves as the active ingredient in antidepressant medications prescribed for various mood and anxiety disorders. Venlafaxine is Second-Generation SNRI; Dual-Action Antidepressant; Racemic API for CNS Applications. Venlafaxine plant have ISO 45001 2018, ISO 9001 2015, ISO 14001 2015 certifications.
Venlafaxine Hydrochloride is a synthetic antidepressant belonging to the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Also known as VENLAFAXINE HCl by manufacturers and fundamentally used to treat major depressive disorder, generalized anxiety disorder and panic disorder. Venlafaxine is a racemic mixture of two enantiomers structurally, each contributing to its pharmacological activity. The Venlafaxine compound is well-absorbed orally and extensively metabolized in the liver, with its active metabolite, O-desmethylvenlafaxine (ODV), also contributing to its therapeutic effects. Venlafaxine supplier employee it in the production of oral dosage forms such as tablets and extended-r...
Chemical Properties & Specifications
Eye Irritation Category 2A; Acute Toxicity Oral Category 4
Warning
H302: Harmful if swallowed. H319: Causes serious eye irritation.
P264: Wash hands thoroughly after handling. P270: Do not eat, drink, or smoke when using this product. P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. P501: Dispose of contents/container in accordance with local regulations.
Used as a frontline antidepressant in the management of Major Depressive Disorder by enhancing the availability of serotonin and norepinephrine in the central nervous system.
Helps reduce excessive worry and tension associated with Generalized Anxiety Disorder, offering long-term relief with minimal sedative effects.
Prescribed for individuals with persistent social fear or avoidance, improving social interaction and quality of life.
Reduces the frequency and intensity of panic attacks by regulating neurotransmitter activity in the brain.
Commonly formulated in extended-release tablets or capsules for once-daily dosing, improving patient compliance.
High oral bioavailability with extensive hepatic metabolism to active metabolite ODV.
Approximately 27% for parent compound; 30% for ODV .
5±2 hours for immediate-release; 15±6 hours for extended-release formulations.
Predominantly renal, with 87% excreted in urine (5% unchanged drug; 29% as ODV; 53% as other metabolites) .
Store at controlled room temperature, 20°C to 25°C (68°F to 77°F); excursions permitted between 15°C and 30°C (59°F to 86°F). Packaging: Available in various quantities suitable for pharmaceutical manufacturing needs.
Available in various quantities suitable for pharmaceutical manufacturing needs.
It acts as a serotonin-norepinephrine reuptake inhibitor (SNRI), used primarily to treat depression, anxiety, and panic disorders by increasing neurotransmitter activity in the brain.
It is an Active Pharmaceutical Ingredient (API), used directly in the formulation of oral antidepressant medications.
It is typically offered at ≥99% purity, suitable for pharmaceutical-grade formulation, with compliance to USP, BP, and EP monographs.
Venlafaxine Hydrochloride is commonly used in extended-release tablets, capsules, and in some cases, immediate-release oral forms.
Suppliers usually offer Certificate of Analysis (COA), MSDS, DMF (Type II), stability data, and residual solvent reports. Pharmacopoeial compliance is mandatory for regulated markets.
Yes, GMP-grade Venlafaxine Hydrochloride is available for use in finished formulations destined for regulated markets.
The API meets standards from US FDA, EDQM, and other national pharmacopeias. CEP and DMF filings may also be available based on the supplier.
MOQ generally starts at 1 kg. Standard lead time ranges from 2–4 weeks, depending on stock and regulatory documentation.
No cold chain is needed, but it must be stored in a cool, dry, well-ventilated area between 20°C and 25°C, away from light and moisture.
It is not export-controlled but classified under GHS as harmful if swallowed and irritating to eyes; standard handling precautions apply.
Yes, Venlafaxine Hydrochloride is frequently used in fixed-dose combinations for anxiety and depression treatment alongside other actives.
