Triphenylphosphine (PPh₃), also known as triphenylphosphane, is an organophosphorus compound featuring a central phosphorus atom bonded to three phenyl groups. Reagent and ligand in organic & organometallic chemistry: fundamentally, it functions as a nucleophile and a reducing agent due to the lone pair of electrons on the phosphorus atom, which is susceptible to oxidation. The compound’s versatility is unsurpassed in its role as a building block for Wittig reagents and as a key component in the Mitsunobu reaction and the Staudinger ligation. A ligand stabilises transition metal catalysts, governing their selectivity and reactivity, a critical function in large-scale industrial synthesis. Also referred to as Triphenylphosphane and Phosphine, Triphenyl Triphenylphosphine suppliers and manufacturers, respectively. We are the leading, trusted Triphenylphosphine supplier worldwide and in the United States, with reliable lead times and global supply capability.
Triphenylphosphine (PPh₃), also known as triphenylphosphane, is an organophosphorus compound featuring a central phosphorus atom bonded to three phenyl groups. Reagent and ligand in organic & organometallic chemistry: fundamentally, it functions as a nucleophile and a reducing agent due to the lone pair of electrons on the phosphorus atom, which is susceptible to oxidation. The compound’s versatility is unsurpassed in its role as a building block for Wittig reagents and as a key component in the Mitsunobu reaction and the Staudinger ligation. A ligand stabilises transition metal catalysts, governing their selectivity and reactivity, a critical function in large-scale industrial synthesis. Also referred to as Triphenylphosphane and Phosphine, Triphenyl Triphenylphosphine suppliers and manufacturers, respectively. We are the leading, trusted Triphenylphosphine supplier worldwide and in the United States, with reliable lead times and global supply capability.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
S26-S36/37/39-S61
R22; R43; R53
H302; H317; H373
P280; P301 + P312 + P330; P333 + P313
Essential reagent in Mitsunobu reaction for forming complex esters and ethers, crucial steps in API synthesis (steroids, peptides)
Synthesis of complex intermediates, certain organophosphorus pesticides & herbicides
Preferred to stabilize and modify transition metal catalysts (e.g., Wilkinson's catalyst) for large-scale polymerization and fine chemical synthesis
Wittig reaction for the stereoselective formation of carbon-carbon double bonds
To reduce azides to amines (Staudinger reaction) and hydroperoxides to alcohols
Acts as a thermal stabilizer in certain polymer systems to prevent degradation during processing
Stable
Incompatible with oxidizing agents, acids
Store at RT