Hero Backgroundrounded-top
rounded-bottom

Rabeprazole Sodium (CAS NO : 117976-90-6)

Rabeprazole Sodium or (Rabeprazole na) a proton pump inhibitor (PPI) that suppresses gastric acid secretion by inhibiting the H⁺/K⁺-ATPase enzyme system at the secretory surface of gastric parietal cells action that leads to a reduction in gastric acidity, providing relief from acid-related disorders. Rabeprazole treats gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. The compound exhibits hygroscopic properties to be specific. Rabeprazole sodium, also known as Rabeprazole sodium salt, is preferred by manufacturers in the pharmaceutical industry for the production of oral dosage forms, such as enteric-coated tablets and capsules, designed to treat acid-related gastrointestinal disorders. Rabeprazole Sodium is a Proton Pump Inhibitor (PPI); Acid-Suppressing Agent; Delayed-Release API for GI Disorders.

Rabeprazole Sodium

Rabeprazole Sodium or (Rabeprazole na) a proton pump inhibitor (PPI) that suppresses gastric acid secretion by inhibiting the H⁺/K⁺-ATPase enzyme system at the secretory surface of gastric parietal cells action that leads to a reduction in gastric acidity, providing relief from acid-related disorders. Rabeprazole treats gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. The compound exhibits hygroscopic properties to be specific. Rabeprazole sodium, also known as Rabeprazole sodium salt, is preferred by manufacturers in the pharmaceutical industry for the production of oral dosage forms, such as enteric-coated tablets and capsules, designed to treat acid-related gastrointestinal disorders. Rabeprazole Sodium is a Proton Pump Inhibitor (PPI); Acid-Suppressing Agent; Delayed-Release API for GI Disorders.

Industries 1Industries

Industry

Pharmaceutical

Category 1Category

Category

Pharmaceutical Actives & Precursors

Sub-categorySub-category 1

Sub-category

Active Pharmaceutical Ingredients (APIs)

Get a Quote

Details included in quote

Minimum Order Quantity

Lead Time

Regional Availability

Incoterms

Intersect 1
Rounded Top

Chemical Properties & Specifications

Applications of Rabeprazole Sodium

Treatment of (GERD)

Used to alleviate symptoms and promote healing in patients with GERD by reducing gastric acid secretion.

Management of (PUD)

Aids in the healing of duodenal and gastric ulcers by inhibiting acid production.

Eradication of Helicobacter pylori Infection

Employed as part of combination therapy to eliminate H. pylori, reducing the risk of ulcer recurrence.

Treatment of Zollinger-Ellison Syndrome

Manages pathological hypersecretory conditions by suppressing excessive gastric acid production.

Formulation in Delayed-Release Tablets

Commonly formulated in enteric-coated tablets to ensure stability and targeted release in the intestine.

Mechanism of Action

Irreversibly binds to and inhibits the H⁺/K⁺-ATPase enzyme system, leading to prolonged suppression of gastric acid secretion.

Bioavailability

Approximately 52% following oral administration.

Protein Binding

Approximately 96.3%.

Metabolism

Extensively metabolized in the liver via CYP2C19 and CYP3A4 isoenzymes.

Elimination Half-Life

Approximately 1 hour.

Excretion

Primarily excreted in urine as metabolites.

Pharmacopoeial Standards: Complies with USP, EP, and BP specifications.

Have Questions About Rabeprazole Sodium?
We've Got Answers.

Our Chemical Products

Get a Quote

Get a Quote