Hero Backgroundrounded-top
rounded-bottom

Itraconazole ITC (CAS NO : 84625-61-6)

Itraconazole is a triazole-class antifungal agent used to treat a variety of fungal infections by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. It is effective against a broad spectrum of fungi, including Aspergillus, Blastomyces, Histoplasma, and Candida species. Itraconazole is also a member of the triazoles class, dioxolane, N-arylpiperazine, dichlorobenzene, cyclic ketal, and aromatic ether. Derived from cis-ketoconazole, its imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group, and the acetyl group on the piperazine moiety is substituted by a p-[(±)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. ECHA deprecated cas number is 84604-65-9.

Itraconazole ITC
Itraconazole ITC

Itraconazole is a triazole-class antifungal agent used to treat a variety of fungal infections by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. It is effective against a broad spectrum of fungi, including Aspergillus, Blastomyces, Histoplasma, and Candida species. Itraconazole is also a member of the triazoles class, dioxolane, N-arylpiperazine, dichlorobenzene, cyclic ketal, and aromatic ether. Derived from cis-ketoconazole, its imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group, and the acetyl group on the piperazine moiety is substituted by a p-[(±)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. ECHA deprecated cas number is 84604-65-9.

Industries 1Industries

Industry

Pharmaceutical

Category 1Category

Category

Pharmaceutical Actives & Precursors

Sub-categorySub-category 1

Sub-category

Active Pharmaceutical Ingredients (APIs)

Fast Response

Get a Quote

Details add in quote!

Minimum Order Quantity

Included in Quote

Lead Time

Included in Quote

Regional Availability

Included in Quote

Incoterms

Included in Quote

Intersect 2
Rounded Top

Chemical Properties & Specifications

Applications of Itraconazole ITC

Medical Treatment

Used to treat systemic and superficial fungal infections, including aspergillosis, blastomycosis, histoplasmosis, and onychomycosis.

Dermatology

Effective in treating dermatophytoses and other cutaneous fungal infections

High Protein Binding therapeutics

Ensures prolonged circulation time and sustained therapeutic levels.

Oral and Topical Administration

Available in multiple formulations to suit different treatment needs.

Fungal infection treatments

Aspergillosis, blastomycosis, histoplasmosis Oral treatments for systemic fungal infections Cosmetic formulations aimed at improving hair growth (in some formulations)

Topical treatments

Onychomycosis

Oral treatments

Systemic fungal infections

Cosmetic formulations

Aimed at improving hair growth (in some formulations)

Have Questions About Itraconazole ITC ?
We've Got Answers.

Itraconazole is an antifungal medication used to treat a variety of fungal infections, including aspergillosis, blastomycosis, histoplasmosis, and onychomycosis. It is also effective for fungal infections of the skin, nails, and internal organs.

Itraconazole is available in capsules, oral solutions, and intravenous forms. The capsules should be taken with a full meal to enhance absorption, while the oral solution is better absorbed on an empty stomach. Always follow your healthcare provider's instructions regarding dosage and administration.

Common side effects include nausea, diarrhea, abdominal pain, rash, and headache. If you experience severe side effects such as liver problems (yellowing of skin or eyes), heart failure symptoms, or severe allergic reactions, seek medical attention promptly.

Yes, certain medications may interact with Itraconazole, leading to serious side effects. Medications like cisapride, pimozide, quinidine, and certain statins (e.g., lovastatin, simvastatin) should not be taken with Itraconazole. Always inform your healthcare provider of all medications and supplements you are using.

The safety of Itraconazole during pregnancy or breastfeeding is not well-established. It is essential to consult your healthcare provider to weigh the potential risks and benefits before using this medication in such situations.

Itraconazole should be stored at room temperature, away from moisture and heat. Keep the medication in its original container, tightly closed, and out of reach of children.

itraconazole, 84625-61-6, Oriconazole, Sporanox, Itrizole, Itrizole (TN), 873066-43-4, Sporanox (TN), ITCZ, Itraconazol, Fungitraxx, Itraconazolo, Itraconazolum, Sporonox, Cladosal 100, 2-butan-2-yl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one, DTXSID3023180, Itraconazole (Sporanox), NSC-759239, Itraconazol [Spanish], Itraconazolum [Latin]

Itraconazole is manufactured globally, with key suppliers and manufacturers located in India, China, and several European countries. These regions are recognized for their large-scale pharmaceutical production capabilities and high-quality manufacturing standards. Leading suppliers in these regions adhere to (GMP), ensuring the consistent quality and regulatory compliance.

The assay specification for Itraconazole typically falls within the range of 98-102%, ensuring its potency and purity for pharmaceutical applications.

High-performance liquid chromatography (HPLC) is commonly used to test the purity and assay of Itraconazole, in line with pharmaceutical standards.

The minimum order quantity (MOQ) for Itraconazole may vary depending on the supplier, but it typically starts from 1 kg for bulk purchases.

Yes, pricing for Itraconazole can be customized based on order volume, frequency, and customer requirements, especially for long-term contracts or bulk orders.

Yes, formulation support is typically available for Itraconazole, particularly for topical formulations, oral solutions, and injectable forms.

Itraconazole is typically cGMP certified, and manufacturers may also hold certifications like USP, EP, and ISO for quality assurance and regulatory compliance.

Yes, documentation such as Certificates of Analysis (COA), GMP compliance certificates, and MSDS are available to confirm the product’s quality and regulatory compliance.

Yes, Itraconazole is available in both base and salt forms, depending on the intended formulation and application.

The preferred grade for Itraconazole export is typically USP grade or EP grade, which ensures compliance with international regulatory standards.

Yes, long-term supply contracts for Itraconazole can be arranged, particularly for pharmaceutical manufacturers, ensuring a steady supply for ongoing production needs.

India, North America, EU preferrably

Our Chemical Products

Chlorantraniliprole 0.4% GR
Top Right Icon

Chlorantraniliprole 0.4% GR

CAS No. : 500008-45-7

Category : Crop Protection & Pest Control

Sub-Category : Insecticides

Description: Chlorantraniliprole is an anthranilic diamide insecticide that targets a broad spectrum of pests, in...

View Product
Pyroxasulfone 85% WG
Top Right Icon

Pyroxasulfone 85% WG

CAS No. : 447399-55-5

Description: Pyroxasulfone is a selective, pre-emergence herbicide that inhibits the biosynthesis of very-long-ch...

View Product
Pymetrozine 50% WG
Top Right Icon

Pymetrozine 50% WG

CAS No. : 123312-89-0

Category : Crop Protection & Pest Control

Sub-Category : Insecticides

Description: Pymetrozine is a selective insecticide belonging to the pyridine azomethine chemical class, primaril...

View Product
Etodolac
Top Right Icon

Etodolac

CAS No. : 41340-25-4

Category : Pharmaceutical Actives & Precursors

Sub-Category : Active Pharmaceutical Ingredients (APIs)

Description: Etodolac is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and an...

View Product
Titanium Dioxide R-2195
Top Right Icon

Titanium Dioxide R-2195

CAS No. : 13463-67-7

Description: R-2195 is a rutile titanium dioxide pigment treated with inorganic silicon and aluminum. It features...

View Product
Fast Response

Get a Quote

Fast Response

Get a Quote