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Thiophenol (CAS NO : 108-98-5)

Thiophenol (Alternate CAS 33411-63-1), also known as Benzenethiol or Phenyl Mercaptan, is a foundational organosulfur building block and the simplest of the aromatic thiols. Characterised by its distinctively pungent, garlic-like odor and high nucleophilic reactivity, it serves as a versatile intermediate in the precision synthesis of pharmaceuticals, agrochemicals, and high-performance polymers. Sulfhydryl (-SH) group on the benzene ring allows for the efficient introduction of sulfur-containing moieties into complex molecular architectures through substitution, addition, and radical reactions. In the pharmaceutical industry, it is a critical precursor for various active ingredients, including antipsychotics and specialised preservatives like Thimerosal. Utility extends to the agrochemical sector for the production of potent insecticides and to materials science, where it is used to develop high-refractive-index monomers and sulfur-bridged photoinitiators. By ensuring high chemical purity and low moisture content, Thiophenol provides manufacturers with a reliable starting material for achieving high-yield, high-selectivity transformations in demanding chemical processes. We are a globally established Thiophenol manufacturer and various other elemental derivatives supplier, along with a broad portfolio of other speciality chemicals worldwide through comprehensive regulatory documentation (CoA), traceability, and consistent global supply capabilities, ensuring reliable lead times and quality assurance across all grades.

Thiophenol

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Thiophenol (Alternate CAS 33411-63-1), also known as Benzenethiol or Phenyl Mercaptan, is a foundational organosulfur building block and the simplest of the aromatic thiols. Characterised by its distinctively pungent, garlic-like odor and high nucleophilic reactivity, it serves as a versatile intermediate in the precision synthesis of pharmaceuticals, agrochemicals, and high-performance polymers. Sulfhydryl (-SH) group on the benzene ring allows for the efficient introduction of sulfur-containing moieties into complex molecular architectures through substitution, addition, and radical reactions. In the pharmaceutical industry, it is a critical precursor for various active ingredients, includ...

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Chemical Properties & Specifications

Applications of Thiophenol

Antipsychotic Synthesis

Key building block for the synthesis of phenothiazine derivatives and other CNS-active agents & Pharmaceutical Synthesis API sulfonamides

Specialty Preservatives

Intermediate for the production of Thimerosal, an organomercury compound widely used as a preservative in vaccines and ophthalmic products

Enzyme Inhibitors

Scaffold in the design of various sulfur-containing enzyme inhibitors and anti-inflammatory candidates

Insecticide Production

Vital precursor for the synthesis of organophosphorus insecticides and acaricides

Herbicide Intermediates

Development of specialized sulfur-containing herbicides that require precise phenyl-thio linkages for biological efficacy

(HRI) Polymers

Synthesises sulfur-rich monomers for high-index optical lenses and coatings

Photoinitiators

Essential component in the manufacture of sulfur-bridged photoinitiators for UV-curable resins and 3D printing applications

Chain Transfer Agent

Radical polymerization to control molecular weight and improve the thermal stability of specialized plastics

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