Search through
Hero Background
rounded-bottom

N,N Carbonyl diimidazole (CDI) (CAS NO : 530-62-1)

Our N,N-Carbonyldiimidazole (CDI) is a high-purity white crystalline reagent engineered to activate carboxylic acids for nucleophilic substitution. Acting as a safer, solid alternative to highly toxic phosgene, CDI facilitates clean reactions by releasing only CO₂ and imidazole as relatively innocuous by-products. In 2026, it is the preferred choice for "Green Chemistry" applications because it eliminates the need for corrosive acid chlorides or strong auxiliary bases, significantly reducing side reactions and simplifying purification. We provide high-stability grades with 99%+ purity, specifically designed to maintain activity in anhydrous environments for critical API, peptide manufacturing, peptide synthesis, protein modification, and pharmaceutical research. Plays a highly crucial role in the synthesis of nucleic acid derivatives and other complex organic molecules. We are a global manufacturer of N,N-carbonyl diimidazole, specialised in producing high-purity (98.97%) CDI with large-scale production capacity, ensuring reliable lead times; comprehensive regulatory documentation (CoA); and consistent worldwide supply capabilities across all grades/forms/purity.

N,N Carbonyl diimidazole (CDI)

Documents

COA
TDS

Our N,N-Carbonyldiimidazole (CDI) is a high-purity white crystalline reagent engineered to activate carboxylic acids for nucleophilic substitution. Acting as a safer, solid alternative to highly toxic phosgene, CDI facilitates clean reactions by releasing only CO₂ and imidazole as relatively innocuous by-products. In 2026, it is the preferred choice for "Green Chemistry" applications because it eliminates the need for corrosive acid chlorides or strong auxiliary bases, significantly reducing side reactions and simplifying purification. We provide high-stability grades with 99%+ purity, specifically designed to maintain activity in anhydrous environments for critical API, peptide manufacturin...

Get a Quote

Details included in quote

Minimum Order Quantity

Lead Time

Regional Availability

Incoterms

Rounded Top

Chemical Properties & Specifications

Applications of N,N Carbonyl diimidazole (CDI)

Peptide Synthesis

Primary coupling agent for amino acid activation with minimal racemisation

Pharmaceutical Intermediates

Essential for the synthesis of antibiotics, anti-inflammatory drugs, and complex bioconjugates

Organic Synthesis

Converts amines into ureas and carbamates, and alcohols into esters

Nucleoside Chemistry

Facilitates the activation of phosphates and the synthesis of nucleic acid derivatives

Polymer Science

Cross-linking agents & for surface functionalisation in advanced material science

Have Questions About N,N Carbonyl diimidazole (CDI)?
We've Got Answers.

Suggested Products

No products found

Get a Quote

Get a Quote