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Scimplify is a global supplier of Fluconazole API in various pharmacopoeial standards. Fluconazole is a triazole antifungal medication used to treat a variety of systemic and superficial fungal infections. Fluconazole functions by inhibiting the fungal cytochrome P450 enzyme 14α-demethylase, disrupting the conversion of lanosterol to ergosterol, an essential component of the fungal cell membrane. This action renders it effective against infections such as candidiasis, cryptococcosis, and coccidioidomycosis, which is critical for Fluconazole api manufacturers and semi finished product formulators. Scimplify pharmaceuticals focuses on manufacturing critical attributes that impact formulation performance and regulatory acceptance rather than finished dosage applications, which include molecule-specific quality control, impurity management, and supply reliability, supporting both development-stage and commercial pharmaceutical requirements for the formulators worldwide. We are a globally established Fluconazole API supplier with 99% Fluconazole purity, along with a broad portfolio of other pharmaceutical apis on various geographies through comprehensive regulatory documentation like the Fluconazole API CoA, traceability, and consistent global supply capabilities, ensuring reliable lead times and quality assurance across all grades.
Scimplify is a global supplier of Fluconazole API in various pharmacopoeial standards. Fluconazole is a triazole antifungal medication used to treat a variety of systemic and superficial fungal infections. Fluconazole functions by inhibiting the fungal cytochrome P450 enzyme 14α-demethylase, disrupting the conversion of lanosterol to ergosterol, an essential component of the fungal cell membrane. This action renders it effective against infections such as candidiasis, cryptococcosis, and coccidioidomycosis, which is critical for Fluconazole api manufacturers and semi finished product formulators. Scimplify pharmaceuticals focuses on manufacturing critical attributes that impact formulation p...
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
Acute Toxicity (Oral): Category 4 Skin Irritation: Category 2 Eye Irritation: Category 2A Reproductive Toxicity: Category 1B Specific Target Organ Toxicity (Single Exposure): Category 3
H302: Harmful if swallowed. H315: Causes skin irritation. H319: Causes serious eye irritation. H360D: May damage the unborn child. H335: May cause respiratory irritation.
P201: Obtain special instructions before use. P280: Wear protective gloves, clothing, and eye protection. P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor if you feel unwell. P302+P352: IF ON SKIN: Wash with plenty of water. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
Used as an active ingredient in antifungal medications for treating infections like candidiasis, cryptococcosis, and other systemic fungal infections.
Employed in studies focusing on antifungal therapies and fungal cell membrane synthesis.
Store at room temperature (typically 15–30°C or 59–86°F).
Keep in a cool, dry, well-ventilated area, away from direct sunlight and moisture.
Store in original, tightly sealed containers to prevent contamination and degradation.
Available in 1 kg, 5 kg, 10 kg, and 25 kg containers. Custom packaging available upon request.
Fluconazole is used to treat and prevent fungal infections such as candidiasis, cryptococcosis, and other systemic mycoses.
It inhibits fungal cytochrome P450 enzyme 14α-demethylase, disrupting ergosterol synthesis, which weakens the fungal cell membrane.
Fluconazole is effective against many fungal infections but may not be suitable for certain resistant strains.
Yes, it is commonly used as a prophylactic antifungal agent for immunocompromised individuals, including chemotherapy and transplant patients.
Common side effects include nausea, headache, dizziness, and gastrointestinal disturbances. Severe reactions are rare but possible.
Yes, Fluconazole can interact with other medications, such as anticoagulants and cytochrome P450 inhibitors. Consult a healthcare provider before use.
Long-term use should be monitored by a healthcare professional to avoid potential liver toxicity and resistance development.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
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