

We are one of the leading manufacturers, distributors, and suppliers of Polysorbate 80 in USA. Its CAS Number is 9005-65-6, and the chemical formula is (C64H124O26)n-multiple grades.
Polysorbate 80 is a nonionic surfactant and emulsifier widely used in pharmaceuticals, food production, and cosmetics. (Alkest TW 80) stabilizes emulsions, enhances solubility of active ingredients, and reduces surface tension in aqueous solutions. Polysorbate 80 is a hydrophilic nonionic surfactant widely used in the pharmaceutical industry as an excipient to stabilize aqueous formulations of injectable medications and vaccines. Polysorbate 80 acts as a solubilizing agent, helping substances that normally wouldn’t dissolve in water to become soluble, which is crucial for parenteral drugs and vaccination formulations. In addition to its pharmaceutical use, Polysorbate 80 also functions as an emulsifier in food products, and In cosmetics/personal care products as an surfactant. PS 80 role as an emulsifier helps mix ingredients and prevent separation, making it a versatile ingredient in both pharmaceutical and consumer products. Polysorbate 80 is approved for use in several vaccines licensed in the USA and plays a key role in maintaining formulation stability. Also refered to as (Kolliphor PS 80, Montanox 80, Alkest TW 80, Kotilen-80, Polyoxyethylene (20) sorbitan monooleate) by speciality chemicals suppliers and manufacturers.


Polysorbate 80, also known as Tween 80, is a nonionic surfactant and emulsifier widely used in industrial applications to blend oil and water-based ingredients. It acts as a useful solubilizer and emulsifier. Polysorbate 80 is commonly used in pharmaceuticals, cosmetics, and food products. As a leading Polysorbate 80 manufacturer in the US, we produce high-purity Tween 80 that meets US standards and certifications, including TSCA and NSF (Wherever applicable). For U.S. manufacturers considering buying polysorbate 80 in bulk, understanding its precise properties is crucial. Polysorbate 80 has a molecular weight of around 1,310 g/mol, and polysorbate 80 has a density of approximately 1.07 g/mL at 25°C. For detailed handling, storage, and emergency information, please refer to our Polysorbate 80 SDS or MSDS in the document section. As a renowned polysorbate 80 supplier and manufacturer in the USA, we offer competitive pricing (USD) and 55lb drum packaging for standard applications, as well as 440 lb barrels for bulk industrial use. Scimplify ensures reliable lead times across U.S regions through our efficient logistics and supply chain teams.
PharmaceuticalIndustrial ChemicalsBeauty & Personal Care
Surfactants & EmulsifiersExcipientsFunctional Ingredients
Functional Emulsifiers
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Chemical Properties & Specifications
Polysorbate 80 is a key food-grade emulsifier that enhances consistency and extends the shelf life of processed foods. In the U.S. food sector, it is widely used in ice creams, whipped toppings, bakery mixes, sauces, and dressings, where it helps maintain a smooth texture and prevents ingredient separation.
Polysorbate is used as a surfactant and emulsifier to blend oil and water components, enabling smooth, uniform lotions and creams. It enhances product stability and texture.
In U.S. pharmaceutical formulations, Polysorbate 80 is used as a solubiliser, stabiliser, and dispersing agent for injectable drugs, vaccines, and oral liquids. It improves ingredient dispersion and protects biologics from aggregation.
In industrial processes, Polysorbate 80 plays a role as a wetting agent, dispersant, and emulsifier in coatings, paints, lubricants, agricultural sprays, and other chemical blends aimed at U.S. manufacturing applications
For laboratories and biotech firms in the U.S., Polysorbate 80 is used to solubilize APIs, stabilise proteins, and act as a surfactant in cell culture, reagent preparation, and diagnostic formulations.

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