

We are one of the leading manufacturers, distributors, and suppliers of Polysorbate 80 in USA. Its CAS Number is 9005-65-6, and the chemical formula is (C64H124O26)n-multiple grades.
Polysorbate 80, also known as Tween 80, is a nonionic surfactant and emulsifier widely used in industrial applications to blend oil and water-based ingredients. It acts as a useful solubilizer and emulsifier. Polysorbate 80 is commonly used in pharmaceuticals, cosmetics, and food products. As a leading Polysorbate 80 manufacturer in the US, we produce high-purity Tween 80 that meets US standards and certifications, including TSCA and NSF (Wherever applicable). For U.S. manufacturers considering buying polysorbate 80 in bulk, understanding its precise properties is crucial. Polysorbate 80 has a molecular weight of around 1,310 g/mol, and polysorbate 80 has a density of approximately 1.07 g/mL at 25°C. For detailed handling, storage, and emergency information, please refer to our Polysorbate 80 SDS or MSDS in the document section. As a renowned polysorbate 80 supplier and manufacturer in the USA, we offer competitive pricing (USD) and 55lb drum packaging for standard applications, as well as 440 lb barrels for bulk industrial use. Scimplify ensures reliable lead times across U.S regions through our efficient logistics and supply chain teams.


Polysorbate 80, also known as Tween 80, is a nonionic surfactant and emulsifier widely used in industrial applications to blend oil and water-based ingredients. It acts as a useful solubilizer and emulsifier. Polysorbate 80 is commonly used in pharmaceuticals, cosmetics, and food products. As a leading Polysorbate 80 manufacturer in the US, we produce high-purity Tween 80 that meets US standards and certifications, including TSCA and NSF (Wherever applicable). For U.S. manufacturers considering buying polysorbate 80 in bulk, understanding its precise properties is crucial. Polysorbate 80 has a molecular weight of around 1,310 g/mol, and polysorbate 80 has a density of approximately 1.07 g/m...
Oleochemicals
Surfactants
Non-ionic Ethoxylates
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Chemical Properties & Specifications
Polysorbate 80 is a key food-grade emulsifier that enhances consistency and extends the shelf life of processed foods. In the U.S. food sector, it is widely used in ice creams, whipped toppings, bakery mixes, sauces, and dressings, where it helps maintain a smooth texture and prevents ingredient separation.
Polysorbate is used as a surfactant and emulsifier to blend oil and water components, enabling smooth, uniform lotions and creams. It enhances product stability and texture.
In U.S. pharmaceutical formulations, Polysorbate 80 is used as a solubiliser, stabiliser, and dispersing agent for injectable drugs, vaccines, and oral liquids. It improves ingredient dispersion and protects biologics from aggregation.
In industrial processes, Polysorbate 80 plays a role as a wetting agent, dispersant, and emulsifier in coatings, paints, lubricants, agricultural sprays, and other chemical blends aimed at U.S. manufacturing applications
For laboratories and biotech firms in the U.S., Polysorbate 80 is used to solubilize APIs, stabilise proteins, and act as a surfactant in cell culture, reagent preparation, and diagnostic formulations.
Polysorbates undergo degradation by auto-oxidation, producing reactive peroxides, in addition to hydrolysis. Exposure to light of polysorbate 80 aqueous solution leads autoxidation of the alkyl polyoxyethylene chain leading to the production of hydroperoxide derivatives. The peroxides cause oxidative damage to the protein molecule that makes up the formulation. The residual peroxides and the rate of peroxide generation as a result of light exposure are found to vary for polysorbate 80 of different grades/from different sources.
Store at room temperature (15–30°C or 59–86°F)
25 kg drums, 200 kg barrels, customized packaging for pharma & food applications