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1-(3-Dimethylaminopropyl)-3-Ethyl Carbodiimide Hydrochloride (EDAC·HCl) is a carbodiimide reagent widely used as a coupling agent in peptide synthesis and in conjugation reactions. It works by activating carboxyl groups on amino acids and facilitating the formation of peptide bonds. EDAC·HCl is particularly important in the creation of biomolecule conjugates, such as when linking haptens to proteins or polypeptides. Additionally, it is used in immobilizing biomolecules for various research applications, including the development of biosensors. Also called (1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride)
1-(3-Dimethylaminopropyl)-3-Ethyl Carbodiimide Hydrochloride (EDAC·HCl) is a carbodiimide reagent widely used as a coupling agent in peptide synthesis and in conjugation reactions. It works by activating carboxyl groups on amino acids and facilitating the formation of peptide bonds. EDAC·HCl is particularly important in the creation of biomolecule conjugates, such as when linking haptens to proteins or polypeptides. Additionally, it is used in immobilizing biomolecules for various research applications, including the development of biosensors. Also called (1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride)
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
EDAC·HCl is extensively used to activate carboxyl groups in peptides, enabling the formation of peptide bonds between amino acids, facilitating the synthesis of peptides and proteins.
It is used to link haptens to carrier proteins, making it essential in the preparation of vaccines and in various immunoassays.
When combined with N-Hydroxysuccinimide (NHS), EDAC·HCl is used for immobilizing biomolecules onto solid supports, which is essential in the fabrication of biosensors and affinity chromatography applications.
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Category : Synergists & Smoke Suppressants
Sub-Category : Antimony-based synergists
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Category : Inorganic Chemicals
Sub-Category : Metal-Based Coagulants
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Category : Inorganic Chemicals
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Category : Pharmaceutical Actives & Precursors
Sub-Category : Active Pharmaceutical Ingredients (APIs)
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Category : Pigments & Colorants
Sub-Category : Inorganic Pigments
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Category : Pigments & Colorants
Sub-Category : Inorganic Pigments
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Category : Pigments & Colorants
Sub-Category : Inorganic Pigments