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1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine (Apremilast Intermediate)

1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine (Apremilast Intermediate)

CAS Number: 253168-94-4

Molecular Formula: C12H19NO4S

Selective Phosphodiesterase 4 (PDE4) InhibitorClinical Indications: Psoriatic Arthritis, Plaque Psoriasis, Behçet's DiseaseBulk aminosulfone manufacturingOtezla intermediate supplyWholesale pharmaceutical building blockGMP Grade apremilast building block

About the product

Apremilast Intermediate (CAS 253168-94-4), chemically identified as 1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine, a pivotal aminosulfone building block. In pharmaceutical landscape, this intermediate serves as the essential chiral precursor for the synthesis of Apremilast (Otezla), a blockbuster oral ther...

1-(3-Ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethylamine (Apremilast Intermediate) Specifications

CAS Number
253168-94-4
Molecular Formula
C12H19NO4S
Molecular Weight
273.35
IUPAC Name
1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethanamine
Canonical SMILES
CCOC1=C(C=CC(=C1)C(CS(=O)(=O)C)N)OC
InChI Key
BXUJVINGXQGNFD-UHFFFAOYSA-N
InChI
1S/C12H19NO4S/c1-4-17-12-7-9(5-6-11(12)16-2)10(13)8-18(3,14)15/h5-7,10H,4,8,13H2,1-3H3
PubChem CID
11288792
MDL Number
MFCD27665207

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