

1,3-Cyclohexadiene (CAS 592-57-4) serves as a critical reactive scaffold within the domestic API intermediates market, where its specialized use in Diels-Alder cycloadditions allows US-based CDMOs to synthesize complex natural products and heterocyclic frameworks with a Pharma/API purity of 99% for high-stakes therapeutic development. 1,2-Dihydrobenzene has seen a surge in demand through domestic custom synthesis services as American manufacturers pivot toward high purity fine chemicals to ensure supply chain resilience and mitigate the volatility of global sourcing shifts, particularly for the production of specialty polymers requiring a 98% general industry purity. 1,3-CHD remains an indispensable building block for any leading US-based bulk chemical supplier catering to the biopharmaceutical sector, where recent trends emphasize the need for rigorous regulatory compliance and the development of advanced fluorescent probes that meet the technical standards expected by the American Chemical Society. We are an established Cyclohexa-1,3-diene intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting Cyclohexa-1,3-diene COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities


1,3-Cyclohexadiene (CAS 592-57-4) serves as a critical reactive scaffold within the domestic API intermediates market, where its specialized use in Diels-Alder cycloadditions allows US-based CDMOs to synthesize complex natural products and heterocyclic frameworks with a Pharma/API purity of 99% for high-stakes therapeutic development. 1,2-Dihydrobenzene has seen a surge in demand through domestic custom synthesis services as American manufacturers pivot toward high purity fine chemicals to ensure supply chain resilience and mitigate the volatility of global sourcing shifts, particularly for the production of specialty polymers requiring a 98% general industry purity. 1,3-CHD remains an indis...
Flavors & Fragrances
Fragrance Ingredients
Terpenes (Dual-Use: Aroma + Flavor)
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Chemical Properties & Specifications
P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P370+P378, P403+P233, P403+P235, P405, and P501
Flam. Liq. 2 (100%), Skin Irrit. 2 (97.7%), Eye Irrit. 2 (97.7%), and STOT SE 3 (100%)
Cyclohexa-1,3-diene serves as a versatile reactive diene and essential building block in Diels-Alder cycloaddition reactions for the construction of complex cyclic and polycyclic frameworks in the synthesis of pharmaceuticals, agrochemicals, and natural products
It is utilized as a precursor in the production of various functionalized molecules, including (diene)iron tricarbonyl complexes, benzene derivatives, and specialized carbocyclic scaffolds for medicinal chemistry
This compound is employed in proteomics research, living anionic polymerization to form polycyclohexadiene, and as a hydrogen donor in transfer hydrogenation processes.
Cyclohexa-1,3-diene is a colorless, flammable liquid organic compound used primarily as a reactive diene in organic synthesis, notably in Diels-Alder reactions to build cyclic and polycyclic frameworks
It is commonly used in the pharmaceutical, agrochemical, and specialty polymer industries as a versatile building block for drug discovery and material science
This compound is compatible with organic solvents and is often used in liquid-phase chemical synthesis and polymerization processes
Standard specifications include CAS number 592-57-4, molecular weight 80.13 g/mol, and purity levels typically around 97%, with documentation such as COA, TDS, impurity reports, and regulatory compliance documents available
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on shipping destination and regulatory requirements.
Category : Fragrance Ingredients
Sub-Category : Polycyclic Synthetic Musks
Description : Our Ambrettolide is a high-purity, 17-membered macrocyclic lactone that captures the elegant, diffus...