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8-Hydroxyquinoline

8-Hydroxyquinoline

CAS Number: 148-24-3

Molecular Formula: C9H7NO

Metal Chelating AgentOLED Material Synthesis (Alq3 Precursor)Antimicrobial Preservative CAS 148-24-3Halquinol I Iodoquinol IntermediateUranium I Thorium Precipitating ReagentBidentate Ligands Scale-up

About 8-Hydroxyquinoline

8-Hydroxyquinoline (8-HQ) (CAS 148-24-3), also known as Oxine, is a versatile heterocyclic chelating agent. In the Elemental Derivatives, Agrochemical, and Pharmaceutical hierarchies, 8-quinolinol serves as a foundational building block for synthesizing a broad spectrum of antimicrobial and antifungal agents. Oxyquinol...

Synonyms

  • Albisal
  • oxychinolil
  • oxyquinolinl
  • phenopyridinl
  • Hydroxychinolin

8-Hydroxyquinoline Specifications

CAS Number
148-24-3
Molecular Formula
C9H7NO
Molecular Weight
145.16
IUPAC Name
quinolin-8-ol
Canonical SMILES
C1=CC2=C(C(=C1)O)N=CC=C2
InChI Key
MCJGNVYPOGVAJF-UHFFFAOYSA-N
InChI
1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H
EINECS Number
205-711-1
MDL Number
MFCD00006807
HSN No
29334900
Molecular Weight
145.16
Melting Point (Experimental)
73-75°C
Boiling Point (Experimental)
~267 °C (approx)
Density (Experimental)
1.034 g/cm³ Temp: 20 °C
pKa (Experimental)
9.66 (pKa2)
Hazard Classes and Categories
Acute Tox. 3 (49.3%), Acute Tox. 4 (50.1%), Skin Sens. 1 (49.6%), Eye Dam. 1 (49.6%), Repr. 1B (40.8%), Aquatic Acute 1 (49.6%), Aquatic Chronic 1 (49.6%)
Precautionary Statement Codes
P203, P261, P264, P264+P265, P270, P272, P273, P280, P301+P316, P302+P352, P305+P354+P338, P317, P318, P321, P330, P333+P317, P362+P364, P391, P405, and P501

Copper Quinolate Backbone

Production of Quinolate fungicides. 8-HQ reacts with copper salts to form Copper-8-quinolinolate, a powerful seed protectant and wood preservative that prevents fungal decay

Antiseptics & Anti-amoebics

Primary APIs for intestinal anti-infectives. 8-HQ Halogenation ring results in potent medicines like Cloxiquine and Halquinols, used in both human and veterinary medicine to treat skin infections and gastrointestinal distress

Metallurgy & Analytical Chemistry High-Selective Chelation

Precipitating agent and extraction reagent in the separation of metals such as aluminum, magnesium, and zinc. Forms insoluble metal-oxinate complexes is vital for Specialty Metal Salts & Reagents.

Detail 1

Stable under normal temperatures; however, it is light-sensitive and can darken over time if exposed to air and UV light

Detail 2

Store in a cool, dry, well-ventilated area

Detail 3

Keep containers tightly closed and protected from light

Detail 4

Recommended storage is 15°C to 25°C

  1. Albisal
  2. oxychinolil
  3. oxyquinolinl
  4. phenopyridinl
  5. Hydroxychinolin

8-Hydroxyquinoline FAQs

Minimum Order Quantity

25 kg (pilot) · 1 MT (commercial)

Lead Time

3 – 5 weeks ex-works

Incoterms

FOB · CIF

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

Regional Availability

India · EU · Middle East · Southeast Asia

Documentation

SDS · COA · TDS available on request

Compliance & Quality

REACH registered*

GHS/SDS available

ISO 9001:2015 site*

RoHS compliant*

Global sourcing network

Consistent quality & reliability

End-to-end technical support

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