

2-Chloro-5-iodobenzoic acid (CAS No: 19094-56-5) serves as a critical bifunctional aromatic building block in the high-growth pharmaceutical and specialty chemical sectors, where its dual halogenation pattern facilitates precise site-selective cross-coupling and nucleophilic substitution reactions. The compound is particularly vital as a key starting material for the synthesis of sodium-glucose co-transporter 2 (SGLT2) inhibitors like Dapagliflozin, as well as various anti-inflammatory and analgesic agents, owing to its ability to streamline complex molecular assembly through efficient carbon-carbon bond formation. Current market trends indicate a significant shift towards high-yield synthetic routes involving methyl o-aminobenzoate and Sandmeyer reactions to achieve commercial-grade purity of 99%, meeting the rigorous quality standards required for global CDMO sourcing and pilot-to-commercial manufacturing. As globally established 2-Chloro-5-iodobenzoic acid supplier with 99% purity, we ensure dependable supply, consistent quality, and complete regulatory documentation, including 2-Chloro-5-iodobenzoic acid CoA and 2-Chloro-5-iodobenzoic acid TDS across all grades. Beyond supply, we support partners through the entire product lifecycle from route scouting, process and formulation development, and analytical method development to scale-up, process optimisation, and pilot-to-commercial manufacturing. Our teams also assist with GMP-compliant quality assurance, regulatory documentation, and global supply chain and logistics coordination.

2-Chloro-5-iodobenzoic acid (CAS No: 19094-56-5) serves as a critical bifunctional aromatic building block in the high-growth pharmaceutical and specialty chemical sectors, where its dual halogenation pattern facilitates precise site-selective cross-coupling and nucleophilic substitution reactions. The compound is particularly vital as a key starting material for the synthesis of sodium-glucose co-transporter 2 (SGLT2) inhibitors like Dapagliflozin, as well as various anti-inflammatory and analgesic agents, owing to its ability to streamline complex molecular assembly through efficient carbon-carbon bond formation. Current market trends indicate a significant shift towards high-yield synthet...

Chemical Properties & Specifications
S26-S39-S45-S60-S61
H301 (86.5%), H315 (15.4%), H318 (82.7%), H319 (15.4%), H335 (13.5%), H400 (82.7%)
3
UN 2811
R25; R41; R50/53
T; N
A key intermediate used in the industrial synthesis of the anti-diabetic drug Dapagliflozin
A useful synthetic intermediate used to prepare metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulators (PAM)
A valuable reagent in cross-coupling reactions for the formation of carbon-carbon bonds in the development of new drugs and materials
An essential building block for the synthesis of various bioactive molecules, anti-inflammatory drugs, and analgesic agents
2-Chloro-5-iodobenzoic acid is an aromatic carboxylic acid utilized as a key synthetic intermediate and building block for the production of bioactive molecules, including anti-diabetic drugs like Dapagliflozin
This compound is widely used in the pharmaceutical, agrochemical, and material science industries for research and the synthesis of complex organic compounds
It is a solid appearing as white to light yellow crystalline powder and is soluble in organic solvents such as methanol and chloroform, but has limited solubility in water
Standard analytical specifications include a CAS number of 19094-56-5, a molecular weight of 282.46, and high purity typically ≥98% or 99% by HPLC, with available documentation including COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a generally accepted MOQ starting from 100 kgs, and lead times for international customers depend on the specific grade and destination.
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