Polysorbate 80 (CAS NO : 9005-65-6)

Polysorbate 80 is a nonionic surfactant and emulsifier widely used in pharmaceuticals, food production, and cosmetics. It stabilizes emulsions, enhances solubility of active ingredients, and reduces surface tension in aqueous solutions. Polysorbate 80 is a hydrophilic nonionic surfactant widely used in the pharmaceutical industry as an excipient to stabilize aqueous formulations of injectable medications and vaccines. It acts as a solubilizing agent, helping substances that normally wouldn’t dissolve in water to become soluble, which is crucial for parenteral drugs and vaccination formulations. In addition to its pharmaceutical use, Polysorbate 80 also functions as an emulsifier in food products such as bread, cake mixes, salad dressings, shortening oils, and chocolate. In cosmetics and personal care products, it serves as a surfactant in soaps and a lubricant in eye drops. Its role as an emulsifier helps mix ingredients and prevent separation, making it a versatile ingredient in both pharmaceutical and consumer products. Polysorbate 80 is approved for use in several vaccines licensed in the USA and plays a key role in maintaining formulation stability.