Phosphorus Oxychloride (POCl3) (CAS NO : 10025-87-3)

Phosphorus Halide and Oxyhalide series-comprising Phosphorus Trichloride (PCl3), Phosphorus Oxychloride (POCl3), and Phosphorus Pentachloride (PCl5)- represents the foundational "workhorse" reagents for modern chemical synthesis. These compounds are indispensable for functional group transformations, particularly in the conversion of alcohols and carboxylic acids into their corresponding chlorides and esters. PCl3 serves as the primary precursor in the phosphorus value chain, essential for the production of plasticizers and organophosphorus pesticides. POCl3 (Phosphory| Chloride) is universally recognized for its role in the Vilsmeier-Haack reaction, enabling the formylation of electron-rich aromatics. PCls acts as a more aggressive chlorinating agent compared to its trivalent counterpart, frequently utilized for the synthesis of acid chlorides from carboxylic acids and for the conversion of amides to nitriles. High-purity grades of these reagents are critical for CDMO operations to ensure high yields and minimize side-product formation (such as phosphoric acid impurities). Due to their extreme sensitivity to moisture and the release of HCl gas upon hydrolysis, these products are handled under strict inert atmospheres (Nitrogen/Argon). We are the leading phosphorus derivatives supplier worldwide, ensuring comprehensive regulatory support & CoA traceability for various grades with global supply capability with reliable lead time.