ZOLEDRONIC ACID

CAS Number: 118072-93-8

Molecular Formula: C5H10N2O7P2

About ZOLEDRONIC ACID

Zoledronic acid (CAS 118072-93-8) serves as a critical nitrogen-containing bisphosphonate specialized for the management of skeletal-related events in oncology and the treatment of systemic metabolic bone diseases, with high purity fine chemicals at pharma/API purity >= 99% being essential to meet stringent U.S. FDA re...

ZOLEDRONIC ACID Specifications

CAS Number

118072-93-8

Molecular Formula

C5H10N2O7P2

Molecular Weight

272.09 g/mol

IUPAC Name

[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid)

Canonical SMILES

C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O.O

InChI Key

XRASPMIURGNCCH-UHFFFAOYSA-N

PubChem CID

68740

CAS Number

118072-93-8

Molecular Formula

C5H10N2O7P2

Molecular Weight

272.09 g/mol

IUPAC Name

[1-hydroxy-2-(1H-imidazol-1-yl)ethane-1,1-diyl]bis(phosphonic acid)

Canonical SMILES

C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O.O

InChI Key

XRASPMIURGNCCH-UHFFFAOYSA-N

PubChem CID

68740

Molecular Weight

272.09 g/mol

Physical appearance

White to almost white powder to crystal

Pharmaceutical

A potent nitrogen-containing bisphosphonate used for the treatment and prevention of osteoporosis in postmenopausal women and men, management of Paget's disease of bone, and treatment of glucocorticoid-induced osteoporosis

Oncology Therapeutic

A critical bone-modifying agent administered to treat hypercalcemia of malignancy and to prevent skeletal-related events, such as pathological fractures and spinal cord compression, in patients with multiple myeloma or bone metastases from solid tumors

Bone Metabolism Regulator

A high-affinity hydroxyapatite-binding compound that inhibits farnesyl pyrophosphate synthase in the mevalonate pathway to suppress osteoclast-mediated bone resorption and increase bone mineral density.