

Trimethyl Borate (CAS No. 121-43-7), also known as TMB, is a high-purity boron ester essential for the US pharmaceutical, electronics, and specialty chemical industries. It serves as the premier boron source for the synthesis of boronic acids and esters used in Suzuki-Miyaura cross-coupling reactions, as well as a critical precursor for chemical vapor deposition (CVD) in semiconductor manufacturing. Our Trimethyl Borate is produced under strict quality management systems and supported by comprehensive documentation, including Certificates of Analysis (CoA), Safety Data Sheets (SDS), and regulatory compliance support for U.S. industrial and research applications. As a reliable Trimethyl Borate manufacturer and supplier in the USA, Scimplify delivers formulation and synthesis-grade material with consistent quality, controlled impurity profiles, and validated batch-to-batch reproducibility with competitive pricing(USD).


Trimethyl Borate (CAS No. 121-43-7), also known as TMB, is a high-purity boron ester essential for the US pharmaceutical, electronics, and specialty chemical industries. It serves as the premier boron source for the synthesis of boronic acids and esters used in Suzuki-Miyaura cross-coupling reactions, as well as a critical precursor for chemical vapor deposition (CVD) in semiconductor manufacturing. Our Trimethyl Borate is produced under strict quality management systems and supported by comprehensive documentation, including Certificates of Analysis (CoA), Safety Data Sheets (SDS), and regulatory compliance support for U.S. industrial and research applications. As a reliable Trimethyl Borat...
Elemental Derivatives
Boron Derivatives
Organo-Borates & Borate Esters
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Chemical Properties & Specifications
In the United States pharmaceutical sector, Trimethyl Borate is used as a specialty reagent and intermediate in API development, medicinal chemistry, and boron-based drug research, supporting FDA-regulated formulation and validation programs.
U.S. agrochemical manufacturers utilize Trimethyl Borate as a boron source and synthetic intermediate in the development of herbicides, fungicides, and plant nutrition formulations designed for EPA-compliant agricultural applications.
Trimethyl Borate serves as an efficient catalyst and cross-linking agent in the production of specialty polymers and resins. It is used to modify the properties of polymers, improving their thermal stability and flame retardancy. Additionally, it is a key reagent in the synthesis of other boron-based specialty chemicals, including borohydrides and various boron-containing catalysts used in industrial chemical manufacturing.
In the American electronics and semiconductor industry, trimethyl borate is used in specialty glass, ceramic precursors, and dielectric materials where controlled boron incorporation is required for insulation, thermal stability, and device reliability.
Trimethyl borate is a versatile organoboron compound with the formula B(OCH3)3, appearing as a colorless, volatile liquid. It is primarily used as a key intermediate in the preparation of sodium borohydride, as a reagent in organic synthesis reactions like Suzuki coupling, and as a solvent for waxes, resins, and oils
This compound is widely used in the chemical manufacturing, metallurgy, textile, wood preservation, and agrochemical industries for applications ranging from synthesis reagents to flame retardants and fungicides
Trimethyl borate is miscible with various organic liquids including alcohol, ether, tetrahydrofuran, hexane, and methanol. It is stable in the absence of moisture but hydrolyzes in the presence of water to form boric acid and methanol
Standard specifications include CAS number 121-43-7, high purity (typically ≥98% or ≥99.5%), and the availability of documentation such as COA, TDS, SDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
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