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2-Chloro-5-iodobenzoic acid (CAS NO : 19094-56-5)

2-Chloro-5-iodobenzoic acid (CAS No: 19094-56-5) serves as a critical bifunctional aromatic building block in the high-growth pharmaceutical and specialty chemical sectors, where American CDMOs increasingly leverage its dual halogenation pattern to facilitate precise site-selective cross-coupling and nucleophilic substitution reactions. This compound has become a vital starting material in the United States for the synthesis of SGLT2 inhibitors like Dapagliflozin, as well as various anti-inflammatory and analgesic agents, due to its ability to streamline complex molecular assembly through efficient carbon-carbon bond formation. Current market trends show a significant shift toward high-yield synthetic routes involving methyl o-aminobenzoate and Sandmeyer reactions to achieve a commercial-grade purity of 99%, meeting the rigorous quality standards required for domestic sourcing and pilot-to-commercial manufacturing. As an established 2-Chloro-5-iodobenzoic acid supplier with 99% purity, we ensure a dependable supply, consistent quality, and complete regulatory documentation, including CoA and TDS across all grades. Beyond supply, we support our partners through the entire product lifecycle—from route scouting, process development, and analytical method development to scale-up, optimization, and full-scale commercial manufacturing. Our teams also provide expert assistance with GMP-compliant quality assurance, regulatory filings, and global supply chain and logistics coordination.

2-Chloro-5-iodobenzoic acid
2-Chloro-5-iodobenzoic acid

2-Chloro-5-iodobenzoic acid (CAS No: 19094-56-5) serves as a critical bifunctional aromatic building block in the high-growth pharmaceutical and specialty chemical sectors, where American CDMOs increasingly leverage its dual halogenation pattern to facilitate precise site-selective cross-coupling and nucleophilic substitution reactions. This compound has become a vital starting material in the United States for the synthesis of SGLT2 inhibitors like Dapagliflozin, as well as various anti-inflammatory and analgesic agents, due to its ability to streamline complex molecular assembly through efficient carbon-carbon bond formation. Current market trends show a significant shift toward high-yield...

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Elemental Derivatives

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Category

Halogen Derivatives

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Sub-category

Iodo/Fluoro-Functional Intermediates

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Chemical Properties & Specifications

Applications of 2-Chloro-5-iodobenzoic acid

Pharmaceutical Intermediate

A key intermediate used in the industrial synthesis of the anti-diabetic drug Dapagliflozin

Synthetic Intermediate

A useful synthetic intermediate used to prepare metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulators (PAM)

Chemical Reagent

A valuable reagent in cross-coupling reactions for the formation of carbon-carbon bonds in the development of new drugs and materials

Organic Building Block

An essential building block for the synthesis of various bioactive molecules, anti-inflammatory drugs, and analgesic agents

Have Questions About 2-Chloro-5-iodobenzoic acid?
We've Got Answers.

2-Chloro-5-iodobenzoic acid is an aromatic carboxylic acid utilized as a key synthetic intermediate and building block for the production of bioactive molecules, including anti-diabetic drugs like Dapagliflozin

This compound is widely used in the pharmaceutical, agrochemical, and material science industries for research and the synthesis of complex organic compounds

It is a solid appearing as white to light yellow crystalline powder and is soluble in organic solvents such as methanol and chloroform, but has limited solubility in water

Standard analytical specifications include a CAS number of 19094-56-5, a molecular weight of 282.46, and high purity typically ≥98% or 99% by HPLC, with available documentation including COA, TDS, impurity reports, and regulatory compliance documents

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a generally accepted MOQ starting from 100 kgs, and lead times for international customers depend on the specific grade and destination.

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