Trifluoroacetic Acid

CAS Number: 76-05-1

Molecular Formula: C2HF3O2

Purity: Trifluoroacetic acid 99% purity

About Trifluoroacetic Acid

Trifluoroacetic Acid (CAS 76-05-1) serves as a critical reagent and specialized solvent in the pharmaceutical industry for peptide synthesis and the production of active pharmaceutical ingredients, with high purity fine chemicals being essential to meet the 99% Pharma/API purity standard required by US-based CDMOs. Per...

Synonyms

Acid, Trifluoroacetic
Cesium Trifluoroacetate
Trifluoroacetate
Trifluoroacetate, Cesium
Trifluoroacetic Acid

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Trifluoroacetic Acid Specifications

CAS Number

76-05-1

Molecular Formula

C2HF3O2

Molecular Weight

114.02 g/mol

IUPAC Name

2,2,2-trifluoroacetic acid

Canonical SMILES

C(=O)(C(F)(F)F)O

InChI Key

DTQVDTLACAAQTR-UHFFFAOYSA-N

InChI

InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

HSN No

29159093

CAS Number

76-05-1

Molecular Formula

C2HF3O2

Molecular Weight

114.02 g/mol

IUPAC Name

2,2,2-trifluoroacetic acid

Canonical SMILES

C(=O)(C(F)(F)F)O

InChI Key

DTQVDTLACAAQTR-UHFFFAOYSA-N

InChI

InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)

HSN No

29159093

melting_point

-15.4 °C

boiling_point

72.4 °C

solubility

Miscible with ether, acetone, ethanol, benzene, carbon tetrachloride, hexane.

density

1.531 at 20 °C

logP

-2.1

Molecular Weight

114.02 g/mol

Purity

Trifluoroacetic acid 99% purity

Organic Synthesis Reagent

A strong acid and versatile reagent widely used as a solvent and catalyst for chemical transformations such as rearrangements, functional group deprotections, oxidations, reductions, and condensations

Pharmaceutical Intermediate

An indispensable building block used in peptide synthesis to remove protecting groups from amino acids and as an intermediate for active pharmaceutical ingredients including antivirals and anti-cancer therapies

Analytical Chromatography Additive

A common ion-pairing agent and mobile-phase additive used in HPLC and LC-MS to improve the separation and analysis of peptides, proteins, and basic compounds