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Triethyl phosphite (CAS NO : 122-52-1)

Triethyl phosphite (CAS 122-52-1) is a vital organophosphorus reagent in the US API intermediates market, serving as a key precursor in the Michaelis-Arbuzov reaction for synthesizing phosphonates used in various pharmaceutical compounds where Pharma/API purity 99% is the benchmark for quality assurance. Phosphorous acid triethyl ester functions as a high purity fine chemical and powerful reducing agent favored by American CDMOs who are increasingly adopting custom synthesis services to enhance domestic supply chain security and meet rigorous American Chemical Society standards for complex molecular assembly. Triethoxyphosphine is also a preferred high-performance additive in the broader industrial sector at General Industry purity 98%, where its role as a ligand in catalytic processes and a stabilizer for polymers makes it essential for a bulk chemical supplier catering to the evolving demands of the US specialty chemicals landscape. We are an established Triethyl phosphite intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting Triethyl phosphite COA/TDS/SDS region-specific regulatory support, reliable lead times, worldwide supply chain capabilities

Triethyl phosphite
Triethyl phosphite

Triethyl phosphite (CAS 122-52-1) is a vital organophosphorus reagent in the US API intermediates market, serving as a key precursor in the Michaelis-Arbuzov reaction for synthesizing phosphonates used in various pharmaceutical compounds where Pharma/API purity 99% is the benchmark for quality assurance. Phosphorous acid triethyl ester functions as a high purity fine chemical and powerful reducing agent favored by American CDMOs who are increasingly adopting custom synthesis services to enhance domestic supply chain security and meet rigorous American Chemical Society standards for complex molecular assembly. Triethoxyphosphine is also a preferred high-performance additive in the broader ind...

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Chemical Properties & Specifications

Applications of Triethyl phosphite

Reducing Agent

A versatile organophosphorus reagent used for the deoxygenation of hydroperoxides to alcohols and in the Corey-Winter olefin synthesis

Organic Synthesis Reagent

A key reactant in the Michaelis-Arbuzov reaction to produce organophosphonates for Horner-Wadsworth-Emmons reactions and in the synthesis of 1-aminocyclopropanephosphonic acid

Phosphine Ligand

A soft ligand employed in coordination chemistry and homogeneous catalysis to form stable complexes with metals like copper(I) iodide, iron, and nickel

Chemical Intermediate

An essential building block for the industrial manufacturing of flame retardants, optical brighteners, antioxidants, and agrochemicals such as insecticides

Polymer Additive

A functional plasticizer, stabilizer, and resin modifier used to enhance the properties of PVC, unsaturated polyesters, and rubber.

Have Questions About Triethyl phosphite?
We've Got Answers.

Triethyl phosphite is an organophosphorus compound and phosphite ester used as a versatile reagent in organic synthesis, a ligand in organometallic chemistry, and a reducing agent

This compound is widely utilized in the agrochemical, pharmaceutical, polymer, and lubricant industries for producing pesticides, flame retardants, plasticizers, and active pharmaceutical ingredients

It is soluble in most organic solvents including ethanol, ether, benzene, and acetone, but is hydrolytically unstable and decomposes in contact with water

Standard specifications include CAS number 122-52-1, high purity (typically ≥98%), boiling point 156°C, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.

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