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tri-Sodium Citrate Dihydrate (CAS NO : 1545801)

tri-Sodium Citrate Dihydrate (CAS 6132-04-3) is a cornerstone of the US API intermediates market, serving as a vital buffering agent and anticoagulant in blood collection systems and parenteral formulations where Pharma/API purity 99% is the benchmark for patient safety and FDA compliance. Trisodium citrate dihydrate has seen a surge in demand from domestic CDMOs who are increasingly seeking custom synthesis services to develop specialized injectable therapies, moving away from volatile global sourcing channels to favor localized, high-purity fine chemicals that meet rigorous American Chemical Society standards. Citric acid trisodium salt dihydrate is also a preferred sequestering agent and stabilizer in the US general industry at a purity of 98%, where its role in specialty food science and advanced detergent formulations requires a bulk chemical supplier capable of providing stringent quality control and comprehensive regulatory documentation. As an established tri-Sodium Citrate Dihydrate suppliers in the united states, we ensure dependable supply, consistent quality, and complete regulatory documentation, including CoA and TDS across all grades. Beyond supply, we support partners through the entire product lifecycle from route scouting, process and formulation development, and analytical method development to scale-up, process optimisation, and pilot-to-commercial manufacturing. Our teams also assist with GMP-compliant quality assurance, regulatory documentation, and global supply chain and logistics coordination

tri-Sodium Citrate Dihydrate

tri-Sodium Citrate Dihydrate (CAS 6132-04-3) is a cornerstone of the US API intermediates market, serving as a vital buffering agent and anticoagulant in blood collection systems and parenteral formulations where Pharma/API purity 99% is the benchmark for patient safety and FDA compliance. Trisodium citrate dihydrate has seen a surge in demand from domestic CDMOs who are increasingly seeking custom synthesis services to develop specialized injectable therapies, moving away from volatile global sourcing channels to favor localized, high-purity fine chemicals that meet rigorous American Chemical Society standards. Citric acid trisodium salt dihydrate is also a preferred sequestering agent and ...

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Chemical Properties & Specifications

Applications of tri-Sodium Citrate Dihydrate

Food Additive

A versatile buffering agent, emulsifier, and preservative used to regulate pH and stabilize texture in products such as processed cheeses, carbonated beverages, and gelatin desserts

Pharmaceutical Excipient

A critical alkalizing and buffering agent utilized in oral rehydration salts, antacids, and syrups to maintain pH stability and enhance drug efficacy

Anticoagulant

A key calcium-chelating agent used in blood collection tubes and blood banks to prevent clotting during storage and transfusions

Laboratory Reagent

A high-purity analytical salt employed as a buffering component in biomolecule downstream processing, chromatography, and the synthesis of metal nanoparticles

Industrial Processing Aid

An effective chelating agent used in detergents for water softening and as a descaling agent for removing carbonate scale from boilers and radiators.

Have Questions About tri-Sodium Citrate Dihydrate?
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tri-Sodium Citrate Dihydrate is a tribasic salt of citric acid that acts as a buffering agent, emulsifier, stabilizer, and preservative. It is widely used to regulate acidity in food and beverages, prevent blood clotting in medical settings, and as a descaling agent in industrial cleaning

This compound is extensively used in the food and beverage, pharmaceutical, personal care, detergent, and industrial cleaning industries

It is highly soluble in water and compatible with aqueous solutions, dry blends, and various processing environments, including both hot and cold conditions

Standard specifications include CAS number 6132-04-3, high purity (typically ≥99%), and documentation such as COA, TDS, impurity reports, and regulatory compliance documents like USP, FCC, and Ph. Eur.

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.

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