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Trans-4-Aminocyclohexanol (4-TAC) is a bicyclic amino alcohol used in synthesizing chiral intermediates for APIs in pharmaceutical industry. For targeting neuroactive agents and selective ligands, the 4-TAC intermediate is currently in drug discovery programs . The trans configuration of 4-TAC gives stereochemical stability for enantioselective synthesis essentials. 4-TAC currently evaluated cyclohexanol for its potential in targeting central nervous system (CNS), analgesic, and anti-inflammatory pathways.
Trans-4-Aminocyclohexanol (4-TAC) is a bicyclic amino alcohol used in synthesizing chiral intermediates for APIs in pharmaceutical industry. For targeting neuroactive agents and selective ligands, the 4-TAC intermediate is currently in drug discovery programs . The trans configuration of 4-TAC gives stereochemical stability for enantioselective synthesis essentials. 4-TAC currently evaluated cyclohexanol for its potential in targeting central nervous system (CNS), analgesic, and anti-inflammatory pathways.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
Eye Irritation: Category 2A Skin Irritation: Category 2 Acute Toxicity (Oral): Category 4
H302: Harmful if swallowed H319: Causes serious eye irritation H315: Causes skin irritation
P280: Wear protective gloves and eye protection P305+P351+P338: IF IN EYES: Rinse cautiously with water P261: Avoid breathing dust/fume P264: Wash hands thoroughly after handling
Used in the synthesis of chiral drug molecules, particularly CNS modulators
Scaffold in the design of selective ligands or inhibitors
Utilized in stereoselective synthesis studies
*Readily available for functionalization and derivatization *Suitable for formulation into custom drug discovery programs
Precursor in the development of neuropharmaceuticals, pain modulators, and specialized CNS drugs
15–30°C
25 kg fiber drums / HDPE jars
2 drums high
2 years in sealed condition
Non-hazardous, standard containerized transport