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Phenylhydrazine Hydrochloride (CAS No. 59-88-1), also known as phenylhydrazinium chloride, is a high-purity aromatic hydrazine salt widely used as a critical intermediate in pharmaceutical synthesis, dye manufacturing, and specialty organic chemical production. It plays an essential role in forming hydrazone derivatives through selective reactions with aldehydes and ketones, enabling the synthesis of active pharmaceutical ingredients, analytical reagents, and functional organic molecules. This compound is supplied as a stable crystalline powder with excellent solubility and controlled impurity profile, ensuring reliable performance in regulated manufacturing environments. Its consistent physicochemical properties and high reactivity make it suitable for GMP intermediates, laboratory research, and industrial chemical synthesis. As an established Phenylhydrazine Hydrochloride manufacturer and supplier in the USA, Scimplify delivers high-purity Phenylhydrazine Hydrochloride (98.76%) with batch-level traceability, COA, SDS, and technical documentation aligned with U.S. regulatory standards. We also ensure consistent supply with reliable lead time and competitive prices (USD).
Phenylhydrazine Hydrochloride (CAS No. 59-88-1), also known as phenylhydrazinium chloride, is a high-purity aromatic hydrazine salt widely used as a critical intermediate in pharmaceutical synthesis, dye manufacturing, and specialty organic chemical production. It plays an essential role in forming hydrazone derivatives through selective reactions with aldehydes and ketones, enabling the synthesis of active pharmaceutical ingredients, analytical reagents, and functional organic molecules. This compound is supplied as a stable crystalline powder with excellent solubility and controlled impurity profile, ensuring reliable performance in regulated manufacturing environments. Its consistent phys...
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
Acute Tox. 3 (96.1%), Acute Tox. 3 (100%), Skin Irrit. 2 (100%), Skin Sens. 1 (100%), Eye Irrit. 2 (100%), Acute Tox. 3 (95.1%), Muta. 2 (100%), Carc. 1A (100%), STOT RE 1 (99%), Aquatic Acute 1 (100%), Aquatic Chronic 1 (37.3%)
P203, P260, P261, P262, P264, P264+P265, P270, P271, P272, P273, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P316, P318, P319, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P391, P403+P233, P405, and P501
Reagent for the Fischer Indole Synthesis, a fundamental reaction in medicinal chemistry used to create the indole core found in triptans (migraine medication) and anti-inflammatory drugs. Used to synthesize Pyrazolones, which serve as the base for various non-steroidal anti-inflammatory drugs (NSAIDs)
Specialty intermediate in the synthesis of Pyrazolate and Phenylpyrazole insecticides and herbicides. High selectivity and low application rates in global cereal and rice farming
Precursor for various organic pigments and solvent dyes. Manufacture of yellow and orange pyrazolone-based pigments for plastics, inks, and coatings
Stable under normal conditions, but can darken (turn pink/red) upon exposure to light and air due to trace oxidation
Store in a cool, dry, dark area. Keep containers tightly closed. It is highly sensitive to moisture; store under an Inert Nitrogen Blanket for extended shelf life
Classified as Hazardous (Class 6.1, Toxic). Available in 25kg fiber drums with double PE liners, compliant with international maritime and air transport regulations
The HCl salt (CAS 59-88-1) is a solid crystalline material with significantly higher stability and a lower rate of oxidation compared to the liquid free base. It is much easier to handle, weigh, and transport in bulk, and it offers a longer shelf life, which is a major advantage for global inventory management.
The pinkish tint is a result of trace oxidation. We minimize this by utilizing high-vacuum distillation for the base before salt formation and by packaging the final product in light-shielded containers under a nitrogen atmosphere. Our COA ensures that the color intensity remains within strictly defined pharmaceutical-grade limits.
Absolutely. Our Phenylhydrazine HCl is optimized for consistent solubility and reactivity. Its high purity ensures that the cyclization step in the Fischer synthesis proceeds with high regioselectivity and minimal by-product formation, which is critical for downstream API purification.
We provide a full regulatory package, including a GHS-compliant SDS, a detailed COA, and documentation for region-specific regulatory compliance, and In USA (TSCA/REACH status) (if applicable). We ensure that all toxicological data is transparently reported to facilitate safe handling at your facility.
The moq to Buy Phenylhydrazinium Chloride Bulk shared with procurement managers.
Phenylhydrazine HCl 99% AR Grade Price. or others shared upon sourcing.
