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PTSU (Tosylurea), is a specialised organic compound that bridges the gap between sulfonyl chemistry and urea-based synthesis. Within the Pharmaceutical, Agrochemical, and Industrial Chemical hierarchies, serves as a high-value building block for the construction of complex heterocyclic rings. Unique molecular architecture - featuring a stable tosyl (Ts) group and a reactive urea functionality - makes it an indispensable intermediate for the synthesis of sulfonylurea-class drugs and highly selective herbicides. Source High-Purity Para Toluene Sulphonyl Urea from Scimplify, a premier global manufacturer and wholesale supplier of sulfonylurea intermediates. Our PTSU is a premium-grade organic building block engineered for the synthesis of next-generation sulfonylurea herbicides and anti-diabetic pharmaceuticals. As an authoritative PTSU manufacturer, we provide a material characterised by its high crystalline stability and low moisture profile, essential for CDMOs and large-scale industrial chemical synthesis. Whether you are developing selective crop protection agents or advanced sulfonylurea-based APIs, our p-Toluenesulfonylurea offers the reactive consistency, global regulatory compliance, and reliable bulk lead times required for global supply chain excellence. Our facility ensures strict adherence to quality protocols, delivering the high-assay material required for complex multi-step organic transformations.
PTSU (Tosylurea), is a specialised organic compound that bridges the gap between sulfonyl chemistry and urea-based synthesis. Within the Pharmaceutical, Agrochemical, and Industrial Chemical hierarchies, serves as a high-value building block for the construction of complex heterocyclic rings. Unique molecular architecture - featuring a stable tosyl (Ts) group and a reactive urea functionality - makes it an indispensable intermediate for the synthesis of sulfonylurea-class drugs and highly selective herbicides. Source High-Purity Para Toluene Sulphonyl Urea from Scimplify, a premier global manufacturer and wholesale supplier of sulfonylurea intermediates. Our PTSU is a premium-grade organic b...
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
Acute Tox. 4 (28.6%)
P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Critical precursor for the synthesis of oral hypoglycemic agents (anti-diabetics) such as Tolbutamide. Sulfonylurea moiety is the pharmacophore responsible for stimulating insulin secretion from pancreatic beta cells
Production of sulfonylurea herbicides, which are known for their low application rates and high selectivity. These herbicides work by inhibiting the ALS (acetolactate synthase) enzyme in weeds, effectively stopping plant growth without harming major cereal crops.
Functional intermediate, to introduce the toluene-sulfonamide structure into specialized resins and polymers, enhancing thermal stability and providing specific chemical resistance in specialty coatings
Stable under normal temperatures; however, it should be protected from strong bases which can cause hydrolysis of the urea linkage
Store in a cool, dry, well-ventilated area. Keep containers tightly closed
Recommended storage: 15°C to 25°C
Non-hazardous for transport in standard crystalline form; available in 25kg fiber drums with double PE liners for international B2B supply
Our PTSU is optimized for low residual p-Toluenesulfonamide levels. High levels of sulfonamide impurities can deactivate catalysts in downstream coupling reactions. By maintaining ≥ 98.5% purity, we help CDMOs reduce the number of purification steps required for the final API
Sulfonylureas are the gold standard for "low-dose" weed control. By providing a high-purity PTSU intermediate, we enable the manufacture of herbicides that require only grams per hectare, significantly reducing the chemical footprint in global agriculture.
Yes. Under specific thermal or catalytic conditions, sulfonyl ureas can serve as "masked" isocyanates, allowing for safer reaction pathways compared to handling free, volatile isocyanates in large-scale reactors.
Absolutely. We provide a full ICP-OES profile for heavy metals (As, Pb, Hg, Cd) upon request, ensuring our material meets the strict ICH Q3D guidelines for elemental impurities in pharmaceutical manufacturing.
No. Because the urea group is already "satisfied," it does not react with water. If your goal is to eliminate bubbles in a polyurethane coating, you must use the liquid(1694-06-0). If your goal is to build a drug molecule, you use the solid PTSU (22663-37-2).
For MOQ to Buy PTS Urea Bulk with shared with procurement managers.
p-Toluenesulfonyl Urea Price 2026 shared upon on sourcing for Bulk PTS Urea for API Manufacturing along with ptsu coa, tds & regulatory compliances.
