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Nepafenac

Nepafenac

CAS Number: 78281-72-8

Molecular Formula: C15H14N2O2

About Nepafenac

Nepafenac (CAS 78281-72-8) is currently a cornerstone of the American ophthalmic pharmaceutical market, primarily utilized as a potent non-steroidal anti-inflammatory drug (NSAID) prodrug to manage pain and inflammation associated with cataract surgery. The 2-Amino-3-benzoylbenzeneacetamide molecule is increasingly bei...

Synonyms

  • 2-amino-3-benzoylbenzeneacetamide
  • nepafenac
  • Nevanac
  • Nepafenac
  • 78281-72-8
View all

Nepafenac Specifications

CAS Number
78281-72-8
Molecular Formula
C15H14N2O2
Molecular Weight
254.28 g/mol
IUPAC Name
2-(2-amino-3-benzoylphenyl)acetamide
Canonical SMILES
C1=CC=C(C=C1)C(=O)C2=CC=CC(=C2N)CC(=O)N
InChI Key
QEFAQIPZVLVERP-UHFFFAOYSA-N
InChI
InChI=1S/C15H14N2O2/c16-13(18)9-11-7-4-8-12(14(11)17)15(19)10-5-2-1-3-6-10/h1-8H,9,17H2,(H2,16,18)
Molecular Weight
254.28 g/mol

Ophthalmic NSAID

A non-steroidal anti-inflammatory drug used for the treatment of pain and inflammation associated with cataract surgery

Anti-inflammatory Prodrug

A topical medication that penetrates the cornea and is converted to amfenac to inhibit COX-1 and COX-2 enzymes

Ophthalmic Suspension

A pharmaceutical formulation applied as eye drops to reduce the risk of macular edema following ocular surgery in diabetic patients

  1. 2-amino-3-benzoylbenzeneacetamide
  2. nepafenac
  3. Nevanac
  4. Nepafenac
  5. 78281-72-8

Nepafenac FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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