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N-Hydroxysulfosuccinimide, sodium salt (NHSS)

N-Hydroxysulfosuccinimide, sodium salt (NHSS)

CAS Number: 106627-54-7

Molecular Formula: C4H4NNaO6S

About N-Hydroxysulfosuccinimide, sodium salt (NHSS)

Sulfo-NHS (CAS 106627-54-7) serves as a critical zero-length crosslinker for the activation of carboxyl groups in aqueous environments, facilitating the formation of stable, water-soluble amine-reactive esters essential for bioconjugation and protein modification. N-Hydroxysulfosuccinimide sodium salt is increasingly i...

N-Hydroxysulfosuccinimide, sodium salt (NHSS) Specifications

CAS Number

106627-54-7

Molecular Formula

C4H4NNaO6S

Molecular Weight

217.13 g/mol

IUPAC Name

sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate

Canonical SMILES

C1C(C(=O)N(C1=O)O)S(=O)(=O)[O-].[Na+]

InChI Key

KOCYJHKDLXPKID-UHFFFAOYSA-M

CAS Number

106627-54-7

Molecular Formula

C4H4NNaO6S

Molecular Weight

217.13 g/mol

IUPAC Name

sodium 1-hydroxy-2,5-dioxopyrrolidine-3-sulfonate

Canonical SMILES

C1C(C(=O)N(C1=O)O)S(=O)(=O)[O-].[Na+]

InChI Key

KOCYJHKDLXPKID-UHFFFAOYSA-M

Molecular Weight

217.13 g/mol

Bioconjugation Reagent

An effective water-soluble crosslinker used for attaching proteins to surfaces or other biomolecules to develop biosensors and diagnostic tools

Protein Modification Agent

A versatile reagent used to convert carboxyl groups to amine-reactive esters in the presence of carbodiimides, enhancing the stability and solubility of proteins for drug delivery systems

Peptide Synthesis Intermediate

A sulfonated additive used in coupling reactions to improve the efficiency of amidations and peptide bond formation

Antibody Labeling Reagent

A specialized chemical employed for labeling antibodies in immunoassays to detect specific proteins in complex biological samples

Environmental Sensor Component

A functional building block explored for the development of sensors to detect pollutants and monitor environmental health.

N-Hydroxysulfosuccinimide, sodium salt (NHSS) FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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