N-Hydroxysuccinimide

CAS Number: 6066-82-6

Molecular Formula: C4H5NO3

Purity: N-Hydroxysuccinimide 98% purity

About N-Hydroxysuccinimide

N-Hydroxysuccinimide (CAS 6066-82-6) serves as a critical activating agent in the United States bioconjugation market, where Pharma/API purity 99% is essential for domestic CDMOs specializing in the development of targeted drug delivery systems and antibody-drug conjugates. 1-Hydroxypyrrolidine-2,5-dione is increasingl...

Synonyms

N-hydroxysuccinimide
N-Hydroxysuccinimide
6066-82-6
1-hydroxypyrrolidine-2,5-dione
HOSu

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N-Hydroxysuccinimide Specifications

CAS Number

6066-82-6

Molecular Formula

C4H5NO3

Molecular Weight

115.09 g/mol

IUPAC Name

1-hydroxypyrrolidine-2,5-dione

Canonical SMILES

C1CC(=O)N(C1=O)O

InChI Key

NQTADLQHYWFPDB-UHFFFAOYSA-N

InChI

InChI=1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2

HSN No

29251900

CAS Number

6066-82-6

Molecular Formula

C4H5NO3

Molecular Weight

115.09 g/mol

IUPAC Name

1-hydroxypyrrolidine-2,5-dione

Canonical SMILES

C1CC(=O)N(C1=O)O

InChI Key

NQTADLQHYWFPDB-UHFFFAOYSA-N

InChI

InChI=1S/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2

HSN No

29251900

Molecular Weight

115.09 g/mol

Purity

N-Hydroxysuccinimide 98% purity

Activating Reagent

A critical reagent for carboxylic acid activation used to form stable, isolable N-hydroxysuccinimide (NHS) esters for efficient amide and ester synthesis

Peptide Synthesis Coupling Agent

A versatile additive used in the carbodiimide method to facilitate smooth coupling reactions between amino acids while minimizing side reactions and simplifying purification due to its high water solubility

Bioconjugation Tool

An essential amine-reactive compound employed for protein labeling with fluorescent dyes, enzymes, and the immobilization of biomolecules onto surfaces such as chromatography supports, nanoparticles, and microarrays

Organic Synthesis Intermediate

A functional building block utilized in the preparation of specialized medicinal compounds, natural products, and functionalized polymers for targeted drug delivery and tissue engineering applications.