N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine

CAS Number: 444731-74-2

Molecular Formula: C13H12ClN5

Purity: N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine 95% purity

About N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine

N-(2-Chloropyrimidin-4-yl)-2,3-dimethyl-2H-indazol-6-amine (CAS 444731-74-2) is a vital building block in the oncology sector, specifically utilized as a key intermediate for the synthesis of the multi-targeted tyrosine kinase inhibitor Pazopanib. As US-based CDMOs increasingly prioritize domestic custom synthesis serv...

Synonyms

444731-74-2
N-(2-CHLOROPYRIMIDIN-4-YL)-2,3-DIMETHYL-2H-INDAZOL-6-AMINE
N-(2-chloro-4-pyrimidinyl)-2,3-dimethyl-2H-Indazol-6-amine
6-[N-(2-chloropyrimidin-4-yl)amino]-2,3-dimethyl-2H-indazole
N-(2-CHLOROPYRIMIDIN-4-YL)-2,3-DIMETHYLINDAZOL-6-AMINE

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N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine Specifications

CAS Number

444731-74-2

Molecular Formula

C13H12ClN5

Molecular Weight

273.72 g/mol

IUPAC Name

N-(2-chloropyrimidin-4-yl)-2,3-dimethylindazol-6-amine

Canonical SMILES

CC1=C2C=CC(=CC2=NN1C)NC3=NC(=NC=C3)Cl

InChI Key

SCUMWVJJSLLWHQ-UHFFFAOYSA-N

InChI

InChI=1S/C13H12ClN5/c1-8-10-4-3-9(7-11(10)18-19(8)2)16-12-5-6-15-13(14)17-12/h3-7H,1-2H3,(H,15,16,17)

PubChem CID

11637631

HSN No

2933990090

CAS Number

444731-74-2

Molecular Formula

C13H12ClN5

Molecular Weight

273.72 g/mol

IUPAC Name

N-(2-chloropyrimidin-4-yl)-2,3-dimethylindazol-6-amine

Canonical SMILES

CC1=C2C=CC(=CC2=NN1C)NC3=NC(=NC=C3)Cl

InChI Key

SCUMWVJJSLLWHQ-UHFFFAOYSA-N

InChI

InChI=1S/C13H12ClN5/c1-8-10-4-3-9(7-11(10)18-19(8)2)16-12-5-6-15-13(14)17-12/h3-7H,1-2H3,(H,15,16,17)

PubChem CID

11637631

HSN No

2933990090

Molecular Weight

273.72 g/mol

Purity

N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine 95% purity

Pharmaceutical Intermediate

An important building block and precursor utilized in the synthesis of Pazopanib, a multi-tyrosine kinase inhibitor used as an antineoplastic agent for the treatment of advanced renal cell carcinoma

Heterocyclic Building Block

A functionalized indazole and pyrimidine derivative employed in organic synthesis for the development of complex molecules and active pharmaceutical ingredients in medicinal chemistry research

Laboratory Reagent

A high-purity chemical compound suitable for R&D applications, including enzymatic assays and kinase inhibition studies in biotechnology and life science industries.