N-((1E)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenyllidene)methanamine (Schiff base)

CAS Number: 79560-20-6

Molecular Formula: C17H15Cl2N

Purity: >95%

Production essential-SSRIs (Selective Serotonin Reuptake Inhibitors)Intermediate for various bioactive moleculesBuilding block in the synthetic pathway of sertralineSchiff base structureSertraline hydrochloride-FDA Approved

About N-((1E)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenyllidene)methanamine (Schiff base)

N-((1E)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenylidene)methanamine (CAS No: 261776-41-4) is a critical high-purity intermediate for North American pharmaceutical manufacturers, specifically utilized in the synthesis of selective serotonin reuptake inhibitors (SSRIs) where its azomethine linkage ensures nece...

N-((1E)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenyllidene)methanamine (Schiff base) Specifications

CAS Number

79560-20-6

Molecular Formula

C17H15Cl2N

Molecular Weight

304.2

IUPAC Name

4-(3,4-dichlorophenyl)-N-methyl-3,4-dihydro-2H-naphthalen-1-imine

Canonical SMILES

ClC1=CC(=CC2=CC(NC)=CC=C2C1)Cl

InChI Key

MGBVAZJASCWJGJ-UHFFFAOYSA-N

InChI

1S/C17H15Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12H,7,9H2,1H3

EINECS Number

616-704-1

MDL Number

MFCD09025945

HSN No

29420090

CAS Number

79560-20-6

Molecular Formula

C17H15Cl2N

Molecular Weight

304.2

IUPAC Name

4-(3,4-dichlorophenyl)-N-methyl-3,4-dihydro-2H-naphthalen-1-imine

Canonical SMILES

ClC1=CC(=CC2=CC(NC)=CC=C2C1)Cl

InChI Key

MGBVAZJASCWJGJ-UHFFFAOYSA-N

InChI

1S/C17H15Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12H,7,9H2,1H3

EINECS Number

616-704-1

MDL Number

MFCD09025945

HSN No

29420090

Molecular Weight

304.2

Solubility in Water

Insoluble

Solubility in Organic Solvents

Soluble in organic solvents such as ethanol, methanol, and acetone

Appearance

Yellow to pale yellow crystalline solid

Odor

Slightly aromatic

Purity

>95%

Boiling Point

390.5ºC (Predicted)

Flash Point

254.9 °C

Density

1.15±0.1 g/cm3

PSA

12.0 Å²

logP

4.6

First Aid Measures

Eye: Wash with plenty of water Skin: Wash with plenty of water Ingestion: Medical assistance for gastric lavage. Inhalation: Remove to fresh air, artificial respiration or oxygen if necessary. Notes to Physician Sertraline Tetralone Methanamine can be washed with plenty of water in case of any exposure

Exposure Controls, Personal Protection

Respiratory: Protection Self-contained breathing apparatus Eye Protection: Wear safety goggles Other Protective Equipment: Protective clothing Skin: Full sleeves apron Clothing: Cotton

Pharmaceutical Synthesis

Serves as a key intermediate in the production of sertraline hydrochloride, an antidepressant medication.

R & D

Utilized in medicinal chemistry studies focused on developing and optimizing antidepressant compounds.

Pharmaceutical Intermediate

An intermediate used in the synthesis of Sertraline or its isotopically labelled versions like Sertraline-d3 for pharmaceutical and medicinal chemistry research

Chemical Reagent

A synthetic compound utilized in industrial and scientific research for the development of new therapeutic agents

Handling

Wear surgical gloves

Storage

~Storage

Conditions to avoid

Direct contract to skin

Packaging Options

Available in various sizes, including 25g, 100g, and 500g, suitable for research and industrial applications.

MSDS

Download

N-((1E)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenyllidene)methanamine (Schiff base) FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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N-((1E)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenyllidene)methanamine (Schiff base)

About N-((1E)-4-(3,4-dichlorophenyl)-3,4-dihydro-1(2H)-naphthalenyllidene)methanamine (Schiff base)