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Montelukast (Free Acid)

Montelukast (Free Acid)

CAS Number: 158966-92-8

Molecular Formula: C35H36ClNO3S

IrritantIrritant
Leukotriene receptor antagonist

About Montelukast (Free Acid)

In the North American generic pharmaceutical manufacturing, contract research, and respiratory formulation sectors, Montelukast Free Acid (CAS No: 158966-92-8)—regularly specified under technical and analytical standards as Montelukast Acid reference standard, CysLT1 antagonist precursor, and high-purity Montelukast fr...

Synonyms

  • Montair
  • Singular
  • Apxi toxin
  • Montelukast Acid
  • (S) Montelukast
View all

Montelukast (Free Acid) Specifications

CAS Number
158966-92-8
Molecular Formula
C35H36ClNO3S
Molecular Weight
586.2 g/mol
IUPAC Name
2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid
Canonical SMILES
CC(C)(C1=CC=CC=C1CC[C@H](C2=CC=CC(=C2)/C=C/C3=NC4=C(C=CC(=C4)Cl)C=C3)SCC5(CC5)CC(=O)O)O
InChI Key
UCHDWCPVSPXUMX-TZIWLTJVSA-N
InChI
InChI=1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-/m1/s1
UNII Code
MHM278SD3E
ChEBI ID
CHEBI:50730
HMDB ID
HMDB0014614
DSSTox Substance ID
DTXSID9023334
EINECS Number
605-168-4
MDL Number
MFCD05662278
Molecular Weight
586.2 g/mol
XLogP3
7.7
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Rotatable Bond Count
12
Exact Mass
585.2104429 Da
Melting Point
275.9 F
GHS Hazard Statements
H302 (50%): Harmful if swallowed H312 (50%): Harmful in contact with skin H332 (50%): Harmful if inhaled

Montelukast Sodium API Synthesis Precursor

Functions as the primary intermediate for base-catalyzed salt formation to produce commercial-grade Montelukast Sodium API

Pharmacopeial Reference Standard & Method Validation

Deployed by pharmaceutical analytical laboratories as a high-purity reference standard for HPLC/chiral method development and forced degradation testing

Asthma & Allergic Rhinitis Therapeutic Intermediate

Generic pharmaceutical manufacturing lines for preparing oral dosage formulations targeting leukotriene-mediated respiratory diseases

CysLT1 Receptor Binding Research Reagent

Actively used in biomedical research to investigate cysteinyl leukotriene pathways, inflammatory signalling, and novel combination therapies

  1. Montair
  2. Singular
  3. Apxi toxin
  4. Montelukast Acid
  5. (S) Montelukast

Montelukast (Free Acid) FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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