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Mifepristone (CAS NO : 84371-65-3)

Mifepristone (CAS 84371-65-3) is a cornerstone of the specialized API intermediates market in the United States, where high purity fine chemicals are increasingly scrutinized under evolving FDA regulatory frameworks and the growing domestic demand for reproductive health therapeutics. RU-486 serves as a high-value molecule for leading American CDMOs who are expanding their custom synthesis services to support onshore pharmaceutical manufacturing and mitigate the complexities of global sourcing shifts. This 11beta-(4-(Dimethylamino)phenyl)-17beta-hydroxy-17alpha-(1-propynyl)estra-4,9-dien-3-one derivative is also a critical subject of research for non-reproductive applications, including oncology and endocrinology, where a bulk chemical supplier must provide Pharma/API purity 99% to satisfy the rigorous technical standards of the American Chemical Society and institutional researchers. We are an established Mifepristone api supplier with >= 99% purity for semi-finished formulators in the united states , providing comprehensive analytical (HPLC/NMR/MS) and supporting (Mifepristone) COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities

Mifepristone
Mifepristone

Mifepristone (CAS 84371-65-3) is a cornerstone of the specialized API intermediates market in the United States, where high purity fine chemicals are increasingly scrutinized under evolving FDA regulatory frameworks and the growing domestic demand for reproductive health therapeutics. RU-486 serves as a high-value molecule for leading American CDMOs who are expanding their custom synthesis services to support onshore pharmaceutical manufacturing and mitigate the complexities of global sourcing shifts. This 11beta-(4-(Dimethylamino)phenyl)-17beta-hydroxy-17alpha-(1-propynyl)estra-4,9-dien-3-one derivative is also a critical subject of research for non-reproductive applications, including onco...

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Pharmaceutical

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Pharmaceutical Actives & Precursors

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Active Pharmaceutical Ingredients (APIs)

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Chemical Properties & Specifications

Applications of Mifepristone

Abortifacient Agent

A synthetic steroidal antiprogestogen used in a combined regimen with misoprostol to induce medical termination of intrauterine pregnancy up to 70 days of gestation

Antiglucocorticoid

A high-dose receptor antagonist utilized to manage and treat hyperglycemia in adult patients with endogenous Cushing syndrome who have type 2 diabetes or glucose intolerance and have failed or are ineligible for surgery

Emergency Contraceptive

A low-dose progesterone receptor modulator employed off-label as a postcoital contraceptive to prevent pregnancy after unprotected intercourse

Gynecological Therapeutic

A selective progesterone receptor antagonist used in clinical research and off-label applications for the medical management of early pregnancy loss, uterine leiomyomas (fibroids), and endometriosis.

Have Questions About Mifepristone?
We've Got Answers.

Mifepristone, also known as RU-486, is a synthetic steroid used primarily for medical termination of pregnancy up to 10 weeks gestation and for managing hyperglycemia in patients with Cushing syndrome

This compound is primarily used in the pharmaceutical and healthcare industries for reproductive health and endocrinology

Mifepristone is commonly formulated as oral tablets and is soluble in DMSO, ethanol, methanol, chloroform, and acetone

Standard specifications include CAS number 84371-65-3, a molecular weight of 429.60, high purity (typically ≥98%), and availability of documentation such as COA, TDS, impurity reports, and regulatory compliance documents

Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time

The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.

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