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Loperamide hydrochloride (CAS 34552-83-5) remains a cornerstone of the American gastrointestinal therapeutic landscape, serving as a high purity fine chemical essential for the formulation of anti-diarrheal medications where Pharma/API purity 99% is required to meet rigorous FDA monographs. The 4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutyramide monohydrochloride segment is seeing significant domestic growth as US-based CDMOs expand their custom synthesis services to address supply chain vulnerabilities and the increasing demand for high-quality over-the-counter and prescription formulations. Loperamide HCl is also a key component in the broader API intermediates market, where its chemical stability and proven efficacy drive its use in diverse pharmaceutical applications, necessitating a reliable bulk chemical supplier capable of navigating the complex US regulatory environment and evolving manufacturing standards. We are an established Loperamide hydrochloride api supplier with >= 99% purity for semi-finished formulators in the united states, providing comprehensive analytical (HPLC/NMR/MS) and supporting Loperamide hydrochloride COA/TDS/SDS region-specific regulatory support, reliable lead times, worldwide supply chain capabilities
Loperamide hydrochloride (CAS 34552-83-5) remains a cornerstone of the American gastrointestinal therapeutic landscape, serving as a high purity fine chemical essential for the formulation of anti-diarrheal medications where Pharma/API purity 99% is required to meet rigorous FDA monographs. The 4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutyramide monohydrochloride segment is seeing significant domestic growth as US-based CDMOs expand their custom synthesis services to address supply chain vulnerabilities and the increasing demand for high-quality over-the-counter and prescription formulations. Loperamide HCl is also a key component in the broader API intermed...
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
P264, P270, P301+P316, P321, P330, P405, and P501
Acute Tox. 3 (100%)
A synthetic mu-opioid receptor agonist used for the symptomatic relief of acute and chronic diarrhea by decreasing intestinal motility and increasing water absorption
A piperidine-derived small molecule utilized as the primary therapeutic component in the formulation of over-the-counter and prescription gastrointestinal medications
A high-affinity peripheral opioid agonist employed in pharmacological studies to investigate opioid receptor signaling, intestinal ion transport, and the role of P-glycoprotein in blood-brain barrier permeability
A chemical compound identified in scientific research for its potential role in inhibiting viral replication processes.
LOPERAMIDE HYDROCHLORIDE is a synthetic phenylpiperidine opioid and mu-receptor agonist used as an antidiarrheal agent to treat acute, chronic, and traveler's diarrhea by slowing intestinal motility
This compound is primarily used in the pharmaceutical, healthcare, and veterinary industries for the production of over-the-counter and prescription gastrointestinal treatments
It is compatible with oral dosage forms including tablets, capsules, orodispersible films, oral solutions, and suspensions, and is freely soluble in methanol and chloroform
Standard specifications include CAS number 34552-83-5, purity of 99-101%, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
Description : P-Nitrobenzoyl Chloride (CAS 122-04-3) is a critical building block in the API intermediates market,...
