LIDOCAINE BASE/HYDROCHLORIDE

CAS Number: 137-58-6

Molecular Formula: C14H22N2O (Lidocaine base) and C14H23ClN2O (Lidocaine hydrochloride)

Purity: Lidocaine 98% purity

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About LIDOCAINE BASE/HYDROCHLORIDE

Lidocaine (CAS 137-58-6) remains a cornerstone of the North American API intermediates market, where its role as an amide-type local anesthetic necessitates a Pharma/API purity 99% to comply with rigorous USP and FDA monographs for injectable and topical formulations. Lignocaine serves as a high purity fine chemical cr...

Variants

Lidocaine

CAS: 137-58-6

LIDOCAINE BASE/HYDROCHLORIDE Specifications

CAS Number

137-58-6

Molecular Formula

C14H22N2O (Lidocaine base) and C14H23ClN2O (Lidocaine hydrochloride)

Molecular Weight

270.80 g/mol

IUPAC Name

2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;hydrochloride

Canonical SMILES

CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI Key

IYBQHJMYDGVZRY-UHFFFAOYSA-N

InChI

InChI=1S/C14H22N2O.ClH/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H

EINECS Number

200-803-8

MDL Number

MFCD00150329

HSN No

29242957

CAS Number

137-58-6

Molecular Formula

C14H22N2O (Lidocaine base) and C14H23ClN2O (Lidocaine hydrochloride)

Molecular Weight

270.80 g/mol

IUPAC Name

2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide;hydrochloride

Canonical SMILES

CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI Key

IYBQHJMYDGVZRY-UHFFFAOYSA-N

InChI

InChI=1S/C14H22N2O.ClH/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H

EINECS Number

200-803-8

MDL Number

MFCD00150329

HSN No

29242957

Molecular Weight

270.80 g/mol

Purity

Lidocaine 98% purity

Melting Point

66-69 °C (Base); 75-79 °C (Hydrochloride Monohydrate); 127-129 °C (Hydrochloride Anhydrous)

Boiling Point

180-182 °C at 4 mmHg; 350.8 °C at 760 mmHg (Predicted)

Freezing point

- Lidocaine: 66-69°C - Lidocaine hydrochloride: 80-82°C

Flash Point

9 °C

Density

0.9944 g/cm3

pKa

7.7 - 7.9

logP

2.44

Vapour pressure

0.144 mPa at 20 °C

Precautionary Statement Codes

P264, P270, P301+P316, P301+P317, P321, P330, P405, and P501

Hazard Classes and Categories

Acute Tox. 3 (82.5%) Acute Tox. 4 (17.5%)

Local Anesthetic

A widely used aminoethylamide that stabilizes neuronal membranes by inhibiting sodium ion fluxes, effectively blocking the initiation and conduction of nerve impulses to provide rapid-onset, intermediate-duration numbing for surgical, dental, and medical procedures

Antiarrhythmic Agent

A Class Ib antiarrhythmic medication administered intravenously to manage acute ventricular tachyarrhythmias and stabilize cardiac membranes by suppressing automaticity in the His-Purkinje system

Topical Analgesic

A versatile active pharmaceutical ingredient formulated into gels, creams, patches, and solutions to relieve pain and itching associated with minor burns, insect bites, postherpetic neuralgia, and mucous membrane irritations