

Levocetirizine dihydrochloride (CAS 130018-87-0) remains a cornerstone in the United States API intermediates market, where the demand for Pharma/API purity of 99% is driven by the increasing prevalence of allergic rhinitis and the strategic expansion of domestic CDMO growth. As a premier bulk chemical supplier, the focus has shifted toward high purity fine chemicals that meet stringent FDA standards for semi-finished therapeutic formulations, particularly as trade uncertainties and new tariff structures on Asian imports necessitate more resilient, US-based sourcing strategies. 2-(2-(4-((R)-(4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid dihydrochloride is increasingly utilized in custom synthesis services to support the development of next-generation, non-sedating antihistamines, reflecting a broader trend of supply chain verticalization among American pharmaceutical manufacturers seeking to mitigate logistical bottlenecks and ensure consistent regulatory compliance. We are an established LEVOCETIRIZINE api supplier with >= 99% purity for semi-finished formulators in the united states, providing comprehensive analytical (HPLC/NMR/MS) and supporting (LEVOCETIRIZINE) COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities

Levocetirizine dihydrochloride (CAS 130018-87-0) remains a cornerstone in the United States API intermediates market, where the demand for Pharma/API purity of 99% is driven by the increasing prevalence of allergic rhinitis and the strategic expansion of domestic CDMO growth. As a premier bulk chemical supplier, the focus has shifted toward high purity fine chemicals that meet stringent FDA standards for semi-finished therapeutic formulations, particularly as trade uncertainties and new tariff structures on Asian imports necessitate more resilient, US-based sourcing strategies. 2-(2-(4-((R)-(4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetic acid dihydrochloride is increasingly utili...
Pharmaceutical
Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
P264, P270, P273, P301+P312, P330, P391, and P501
Acute Tox. 4 (98.2%)
Aquatic Acute 1 (88.3%)
A potent and selective H1-receptor antagonist used for the symptomatic relief of allergic rhinitis, including seasonal and perennial variants, and the treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
An R-enantiomer of cetirizine dihydrochloride utilized in the formulation of oral tablets and solutions to inhibit histamine-induced effects such as sneezing, rhinorrhea, and pruritus
A therapeutic compound that modulates the allergic response by inhibiting the release of pro-inflammatory cytokines, eicosanoids, and limiting eosinophil recruitment at clinically relevant concentrations.
LEVOCETIRIZINE is a second or third-generation antihistamine used for the symptomatic relief of allergic rhinitis, hay fever, and chronic idiopathic urticaria by blocking the action of histamine in the body
It is primarily used in the pharmaceutical industry for the production of allergy medications and respiratory treatments
This ingredient is compatible with oral tablets, oral solutions, fast-dissolving films, and orally disintegrating tablets
Standard specifications include CAS number 130018-87-0, high purity (typically ≥98%), and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
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