Lamivudine

CAS Number: 134678-17-4

Molecular Formula: C8H11N3O3S

Purity: 98% purity

About Lamivudine

Lamivudine (CAS 134678-17-4) serves as a fundamental nucleoside reverse transcriptase inhibitor in the United States pharmaceutical sector, where high purity fine chemicals with >= 99% API grade specifications are mandated for the formulation of critical HIV-1 and chronic Hepatitis B therapies. 3TC (134678-17-4) market...

Synonyms

2',3' Dideoxy 3' thiacytidine
2',3'-Dideoxy-3'-thiacytidine
2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-
3TC Lamivudine
BCH 189

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Lamivudine Specifications

CAS Number

134678-17-4

Molecular Formula

C8H11N3O3S

Molecular Weight

229.26 g/mol

IUPAC Name

4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

Canonical SMILES

C1=CN([C@@H]2CS[C@H](CO)O2)C(=O)N=C1N

InChI Key

JTEGQNOMFQHVDC-NKWVEPMBSA-N

PubChem CID

60825

CAS Number

134678-17-4

Molecular Formula

C8H11N3O3S

Molecular Weight

229.26 g/mol

IUPAC Name

4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

Canonical SMILES

C1=CN([C@@H]2CS[C@H](CO)O2)C(=O)N=C1N

InChI Key

JTEGQNOMFQHVDC-NKWVEPMBSA-N

PubChem CID

60825

Molecular Weight

229.26 g/mol

Purity

98% purity

Physical appearance

White to off-white crystalline solid or powder

Antiviral Agent

A nucleoside reverse transcriptase inhibitor (NRTI) primarily utilized as a cornerstone in antiretroviral therapy (ART) for the treatment of human immunodeficiency virus (HIV-1 and HIV-2) infections and chronic hepatitis B virus (HBV) infection in both adult and pediatric populations

Pharmaceutical Intermediate

A synthetic nucleoside analogue and cytidine derivative used as an active pharmaceutical ingredient (API) in the formulation of oral tablets and solutions, often in fixed-dose combinations with other antiretrovirals like zidovudine or abacavir

DNA Synthesis Inhibitor

A chemical tool used in molecular biology and virology research to study viral replication mechanisms through competitive inhibition of viral DNA polymerase and reverse transcriptase, leading to DNA chain termination.

2',3' Dideoxy 3' thiacytidine
2',3'-Dideoxy-3'-thiacytidine
2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-
3TC Lamivudine
BCH 189