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1-Methyl-3-phenylpiperazine (CAS 5271-27-2) is a critical high-purity fine chemical utilized extensively within the US API intermediates market as the primary building block for the antidepressant Mirtazapine, where achieving a Pharma/API purity 99% is essential to minimize complex impurity profiles during downstream synthesis. N-Methyl-3-phenylpiperazine serves as a versatile heterocyclic scaffold for North American custom synthesis services and CDMOs focusing on central nervous system (CNS) therapeutic pipelines, particularly as domestic manufacturers seek to mitigate global sourcing shifts by securing a reliable bulk chemical supplier capable of meeting rigorous FDA quality standards. 4-Methyl-2-phenylpiperazine remains a foundational component for general industry purity 98% applications, including advanced materials science and biochemical assays, reflecting a growing trend among US-based research institutions to prioritize domestic chemical supply chains that provide comprehensive technical and analytical documentation. We are an established l-Methyl 3-Phenyl Piperazine intermediates supplier with >= 99% purity in the united states, ensuring minimal carry-over of impurities in the final API, and a broad range of various pharmaceutical intermediates for API manufacturers and finished formulators, providing comprehensive analytical (HPLC/NMR/MS) and supporting l-Methyl 3-Phenyl Piperazine COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities
1-Methyl-3-phenylpiperazine (CAS 5271-27-2) is a critical high-purity fine chemical utilized extensively within the US API intermediates market as the primary building block for the antidepressant Mirtazapine, where achieving a Pharma/API purity 99% is essential to minimize complex impurity profiles during downstream synthesis. N-Methyl-3-phenylpiperazine serves as a versatile heterocyclic scaffold for North American custom synthesis services and CDMOs focusing on central nervous system (CNS) therapeutic pipelines, particularly as domestic manufacturers seek to mitigate global sourcing shifts by securing a reliable bulk chemical supplier capable of meeting rigorous FDA quality standards. 4-M...
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Intermediates & Precursors
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Chemical Properties & Specifications
P264, P264+P265, P270, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P321, P330, P332+P317, P362+P364, and P501
Acute Tox. 4 (100%)
Skin Irrit. 2 (100%)
A key building block and essential starting material used in the synthesis of the antidepressant drug Mirtazapine and other tetracyclic medicinal compounds
A reagent utilized in academic and industrial research for organic synthesis, specifically in the development of substituted piperazine derivatives and complex bioactive molecules.
l-Methyl 3-Phenyl Piperazine, also known as 1-Methyl-3-phenylpiperazine or MePP, is a phenylpiperazine derivative that serves as a key chemical intermediate, most notably as a precursor in the synthesis of the antidepressant drug Mirtazapine
This compound is primarily utilized in the pharmaceutical industry for drug synthesis and neurological research, as well as in the agrochemical and specialty chemical sectors as a building block for organic synthesis
It is soluble in acetone, ethanol, and toluene, and sparingly soluble in DMSO and PBS (pH 7.2), making it suitable for liquid-phase organic synthesis and analytical applications
Standard specifications include CAS number 5271-27-2, high purity (typically ≥98%), a melting point of 58-62°C, and available documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the shipping destination and specific grade.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
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