Itraconazole is a triazole-class antifungal agent used to treat a variety of fungal infections by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. Itraconazole or Oriconazole is effective against a broad spectrum of fungi, including Aspergillus, Blastomyces, Histoplasma, and Candida species. Manufacturers named Itraconazole as (Itrizole), which is also a member of the triazoles class, dioxolane, N-arylpiperazine, dichlorobenzene, cyclic ketal, and aromatic ether. Derived from cis-ketoconazole, Itraconazole's imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group, and the acetyl group on the piperazine moiety is substituted by a p-[(±)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. ECHA deprecated cas number is 84604-65-9 for Itraconazole. Itraconazole is specifically FDA Approved and is in WHO Essential Medicines List.
Itraconazole is a triazole-class antifungal agent used to treat a variety of fungal infections by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. Itraconazole or Oriconazole is effective against a broad spectrum of fungi, including Aspergillus, Blastomyces, Histoplasma, and Candida species. Manufacturers named Itraconazole as (Itrizole), which is also a member of the triazoles class, dioxolane, N-arylpiperazine, dichlorobenzene, cyclic ketal, and aromatic ether. Derived from cis-ketoconazole, Itraconazole's imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group, and the acetyl group on the piperazine moiety is substituted by a p-[(±)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. ECHA deprecated cas number is 84604-65-9 for Itraconazole. Itraconazole is specifically FDA Approved and is in WHO Essential Medicines List.
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Pharmaceutical
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Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
Used to treat systemic and superficial fungal infections, including aspergillosis, blastomycosis, histoplasmosis, and onychomycosis.
Effective in treating dermatophytoses and other cutaneous fungal infections
Ensures prolonged circulation time and sustained therapeutic levels.
Available in multiple formulations to suit different treatment needs.
Aspergillosis, blastomycosis, histoplasmosis Oral treatments for systemic fungal infections Cosmetic formulations aimed at improving hair growth (in some formulations)
Onychomycosis
Systemic fungal infections
Aimed at improving hair growth (in some formulations)
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