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Itraconazole ITC

Itraconazole ITC

CAS Number: 84625-61-6

Molecular Formula: C35H38Cl2N8O4

Broad spectrum antifungal agentInhibits Ergosterol SynthesisHigh Protein BindingLimited CNS PenetrationEU EMA regulatedWide Fungak Pathogen EffectivenessFDA Approved / WHO Essential Medicines ListItraconazole Plant ISO CompliantGrade: IP/USP/BP/EP

About Itraconazole ITC

Itraconazole is a triazole-class antifungal agent used to treat a variety of fungal infections by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. Itraconazole, or Oriconazole, is effective against a broad spectrum of fungi, including Aspergillus, Blastomyces, Histoplasma, and Ca...

Synonyms

  • Itraconazole
  • Orungal
  • R 51211
  • R-51211
  • R51211
View all

Itraconazole ITC Specifications

CAS Number
84625-61-6
Molecular Formula
C35H38Cl2N8O4
Molecular Weight
705.63 g/mol
IUPAC Name
2-butan-2-yl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
Canonical SMILES
CCC(C)N1C=NC(=O)N1C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5C(CO5)C6=CC(=C(C=C6)Cl)Cl
InChI Key
XEFQLINVKFYRCS-UHFFFAOYSA-N
InChI
1S/C35H38Cl2N8O4/c1-5-11-30-17-47-35(49-30)34(45-19-39-20-46-45)33(31(36)18-32(37)35)21-43-25-9-7-23(8-10-25)27-13-15-42(16-14-27)24-6-12-26(13)44-28(24)22-41-29(38)48-34/h6-12,19-20,30-31,33H,5,14-18,21-22H2,1-4H3
PubChem CID
55283
EINECS Number
258-110-3
MDL Number
MFCD00870168
UNSPSC Code
51201502
eClass
3788-11-11
HSN No
293499 / 30049099 (formulated)
Molecular Weight
705.63 g/mol
Appearance
White to off-white crystalline powder
Melting Point
166–170°C
Solubility
Practically insoluble in water; soluble in dichloromethane and methanol
Stability
Stable under recommended storage conditions; sensitive to light and moisture
Boiling Point
Decomposes before boiling
GHS Classification GHS Classification
Acute Toxicity (Oral): Category 4, Skin Irritation: Category 2, Eye Irritation: Category 2A, Specific Target Organ Toxicity (Single Exposure): Category 3
(H) Statements
H302, H315, H319, H335: May cause respiratory irritation.
(P) Statements
P261, P264, P270, P301+P312, P302+P352, P305+P351+P338

Medical Treatment

Used to treat systemic and superficial fungal infections, including aspergillosis, blastomycosis, histoplasmosis, and onychomycosis.

Dermatology

Effective in treating dermatophytoses and other cutaneous fungal infections

High Protein Binding therapeutics

Ensures prolonged circulation time and sustained therapeutic levels.

Oral and Topical Administration

Available in multiple formulations to suit different treatment needs.

Fungal infection treatments

Aspergillosis, blastomycosis, histoplasmosis Oral treatments for systemic fungal infections Cosmetic formulations aimed at improving hair growth (in some formulations)

Topical treatments

Onychomycosis

Oral treatments

Systemic fungal infections

Cosmetic formulations

Aimed at improving hair growth (in some formulations)

Temperature

Store at 15–25°C (59–77°F).

Environment

Keep in a cool, dry place, protected from light and moisture.

Protection

Store in tightly sealed, light-resistant containers.

Packaging Options

Available in 100 mg capsules, oral solutions, and topical formulations, packaged in blister packs or bottles.

COA
Download
MSDS
Download
  1. Itraconazole
  2. Orungal
  3. R 51211
  4. R-51211
  5. R51211

Itraconazole ITC FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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