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Isopropyl chloroformate (CAS NO : 108-23-6)

Isopropyl Chloroformate (CAS 108-23-6) is a highly reactive, moisture-sensitive organochlorine compound that serves as a cornerstone reagent in modern organic synthesis. In Elemental Derivatives as (Chlorine/Oxygenated Organics), IPCF is a primary "Acylating Agent." ISOPROPYL CHLOROCARBONATE is indispensable for the introduction of the isopropyl carbonate functional group and for the activation of carboxylic acids. In pharmaceutical sector, a critical building block for the synthesis of Carbonate and Carbamate prodrugs, which are essential for enhancing the bioavailability of oral medications. CDMOs rely on IPCF for the production of specialised peroxydicarbonates used as initiators in polymer science. Given its reactivity, our "Exclusive Grade" is manufactured and stabilised to ensure low acidity and consistent molarity, providing B2B partners with the reliability needed for large-scale regulated manufacturing. We are a globally established bulk IPCF supplier and various other pharmaceutical API, intermediates, and finished dosages-formulations worldwide through comprehensive regulatory documentation (CoA), traceability, and consistent global supply capabilities, ensuring reliable lead times and quality assurance across all grades.

Isopropyl Chloroformate (CAS 108-23-6) is a highly reactive, moisture-sensitive organochlorine compound that serves as a cornerstone reagent in modern organic synthesis. In Elemental Derivatives as (Chlorine/Oxygenated Organics), IPCF is a primary "Acylating Agent." ISOPROPYL CHLOROCARBONATE is indispensable for the introduction of the isopropyl carbonate functional group and for the activation of carboxylic acids. In pharmaceutical sector, a critical building block for the synthesis of Carbonate and Carbamate prodrugs, which are essential for enhancing the bioavailability of oral medications. CDMOs rely on IPCF for the production of specialised peroxydicarbonates used as initiators in polym...

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Pharmaceutical

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Pharmaceutical Actives & Precursors

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Intermediates & Precursors

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Chemical Properties & Specifications

Applications of Isopropyl chloroformate

Peptide Synthesis

Activates carboxylic acids to form mixed anhydrides, a key step in peptide bond formation

Prodrug Development

Essential for creating isopropoxycarbonyloxy (POC) groups, which improve the lipophilicity of polar drug molecules

Protecting Groups

Protects amino and hydroxyl groups during multi-step synthesis, easily removed under mild acidic or basic conditions

Peroxydicarbonates

Precursor for Diisopropyl Peroxydicarbonate (IPP), a vital free-radical initiator used in the polymerization of PVC and optical resins

Carbamate Herbicides

Precursor for various carbamate-based active ingredients that regulate plant growth and manage resistant weed species

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