

Glimepiride (CAS 93479-97-1) continues to be a cornerstone within the United States API intermediates market, where the demand for high purity fine chemicals with Pharma/API purity 99% is driven by the domestic prevalence of type 2 diabetes and the necessity for rigorous USP/NF compliance. Amaryl, as the primary brand reference, has catalyzed a shift toward advanced custom synthesis services in the US, with domestic CDMO growth accelerating as manufacturers seek to mitigate global sourcing risks and prioritize supply chain resilience through onshore production. 1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea remains a high-volume requirement for any US-based bulk chemical supplier catering to the pharmaceutical sector, especially as current trends emphasize the development of complex fixed-dose combination therapies that require ultra-low impurity profiles to meet stringent FDA quality mandates. We are an established Glimepiride api supplier with >= 99% purity for semi-finished formulators in the united states, providing comprehensive analytical (HPLC/NMR/MS) and supporting (Glimepiride) COA/TDS/SDS region-specific regulatory support. reliable lead times, worldwide supply chain capabilities


Glimepiride (CAS 93479-97-1) continues to be a cornerstone within the United States API intermediates market, where the demand for high purity fine chemicals with Pharma/API purity 99% is driven by the domestic prevalence of type 2 diabetes and the necessity for rigorous USP/NF compliance. Amaryl, as the primary brand reference, has catalyzed a shift toward advanced custom synthesis services in the US, with domestic CDMO growth accelerating as manufacturers seek to mitigate global sourcing risks and prioritize supply chain resilience through onshore production. 1-[[p-[2-(3-ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(trans-4-methylcyclohexyl)urea remains a high-vo...
Pharmaceutical
Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
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Chemical Properties & Specifications
P201, P202, P261, P264, P270, P271, P280, P281, P301+P310, P302+P352, P304+P340, P305+P351+P338, P308+P313, P311, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Acute Tox. 3 (37.5%)
Eye Irrit. 2 (62.5%)
Glimepiride is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes by stimulating pancreatic beta cells to release insulin and increasing peripheral insulin sensitivity
This second-generation sulfonylurea is used in clinical studies and comparative trials to evaluate glycemic efficacy, cardiovascular safety, and its role as a second-line therapy in combination with metformin or insulin
Glimepiride serves as a research tool to study ATPase-dependent potassium channel blocking in pancreatic cells and to investigate extrapancreatic effects such as GLUT4 transport protein activation in fat and muscle tissues
Glimepiride is a second-generation sulfonylurea medication used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus by stimulating insulin release from the pancreas
This product is primarily used in the pharmaceutical and healthcare industries for the treatment of metabolic disorders
Glimepiride is typically formulated as oral tablets and is compatible with various pharmaceutical excipients used in solid dosage forms
Standard specifications include high purity, CAS number 93479-97-1, and documentation such as COA, TDS, impurity reports, and regulatory compliance documents
Scimplify has capabilities for global distribution and custom synthesis through an integrated network of manufacturers and logistics partners with reliable lead time
The product is export ready with a standard MOQ starting from 100 kgs, with lead times for international customers depending on the specific shipping destination and regulatory requirements.
Category : Pharmaceutical Actives & Precursors
Sub-Category : Intermediates & Precursors
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