Fexofenadine Hydrochloride

Fexofenadine Hydrochloride

CAS Number
153439-40-8
Molecular Formula
C₃₂H₃₉NO₄ ·HCl
Purity
≥98%
Non-SedativeFast ActingLow Drug InteractionREACH Compliance (EU)Allergy Treatment FDA approvedTherapeutic category: AntihistamineGrade: USPSecond-generation H1 receptor antagonist

About Fexofenadine Hydrochloride

Fexofenadine Hydrochloride is a second-generation, non-sedating antihistamine that selectively inhibits peripheral H1-receptors. Physicians prefer Fexofenadine or FEXOFENADINE HCL to alleviate symptoms associated with allergic rhinitis, urticaria, and seasonal allergies, as it causes minimal central nervous system pene...

Synonyms

  • Allegra
  • alpha-(4-(1-carboxy-1-methylethyl)phenyl)-4-hydroxydiphenylmethyl-1-piperidinebutanol
  • fexofenadine
  • fexofenadine hydrochloride
  • MDL 16,455A

Fexofenadine Hydrochloride Specifications

CAS Number
153439-40-8
Molecular Formula
C₃₂H₃₉NO₄ ·HCl
Molecular Weight
538.12 g/mol
IUPAC NameORBotanical Name
(±)-4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethylbenzeneacetic acid hydrochloride
Canonical SMILES
CC(C)(C(=O)C1=CC=C(C=C1)C(=O)N2CCN(CC2)C3=CC=CC=C3)C4=CC=C(C=C4)O.Cl
InChI Key
RRJFVPUCXDGFJB-UHFFFAOYSA-N
InChI
1S/C32H39NO4.ClH/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27;/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36);1H
EINECS Number
620-701-5
MDL Number
MFCD04241652
UNSPSC Code
51181606
eClass
38012501
NACRES
NA.47
HSN No
2933.99.90
Molecular Weight
538.12 g/mol
solubility
soluble in water, very slightly soluble in acetone.
Purity
≥98%
Form
Crystalline Solid
Color
White to off-white
Odor
Odorless
LogP
4.3
pKa
9.44 (predicted)
Shelf Life
2–3 years
Hazard Statements
H302: Harmful if swallowed H315: Causes skin irritation H319: Causes serious eye irritation
Precautionary Statements
P264: Wash hands thoroughly after handling P270: Do not eat, drink, or smoke when using this product P280: Wear protective gloves/protective clothing/eye protection/face protection P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
First Aid and Emergency Measures
Inhalation: Remove to fresh air, seek medical attention if symptoms persist. Skin Contact: Wash with soap and water. Seek medical advice if irritation persists. Eye Contact: Rinse immediately with water for at least 15 minutes. Seek medical attention if symptoms persist. Ingestion: Rinse mouth. Do not induce vomiting unless advised by a medical professional. Seek immediate medical attention.
GHS Classification
Acute Toxicity (Oral) Category 4 Skin Irritation (Category 2) Eye Irritation (Category 2A)

Pharmaceuticals

Used in the treatment of seasonal allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives).

Healthcare

Can be used as a symptom reliever for allergic reactions caused by pollen, dust mites, animal dander, and insect stings.

Consumer Health

Available in over-the-counter formulations for allergy relief.

Temperature

Store at 20–25°C (68–77°F).

Environment

Keep in a cool, dry place away from light and moisture.

Protection

Use airtight containers to prevent contamination and degradation.

Packaging

Available in blister packs, bottles, and sachets for individual or bulk consumption.

Typical Quantities

Small-scale: 10 mg, 20 mg, 30 mg tablets in bottles or blister packs. Bulk-scale: 100 mg to 500 mg tablets in larger containers for industrial use.

  1. Allegra
  2. alpha-(4-(1-carboxy-1-methylethyl)phenyl)-4-hydroxydiphenylmethyl-1-piperidinebutanol
  3. fexofenadine
  4. fexofenadine hydrochloride
  5. MDL 16,455A

Fexofenadine Hydrochloride FAQs

Minimum Order Quantity

25 kg (evaluation) · 1 MT (commercial)

Lead Time

3 – 5 weeks estimated

Delivery Terms

FOB*

Packaging

20 L pails, 200 L HDPE drums, 1000 L IBC

US Availability

US Facility Inventory

Documentation

US SDS · COA · TDS · Specification sheet

US Regulatory & Quality Information

TSCA status*

US SDS / HazCom*

GHS classification*

ISO 9001:2015 site*

DOT shipping classification*

FDA status*

EPA status*

California Prop 65*

Reliable US supply chain

Regulatory compliance

On-time delivery

Technical expert support

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