Fexo Base Fexofenadine (Freebase)

CAS Number: 83799-24-0

Molecular Formula: C32H39NO4

Purity: 99.50%

About Fexo Base Fexofenadine (Freebase)

Fexo Base Fexofenadine (Freebase) also known as Fexo-Base, is an advanced pharmaceutical intermediate with the CAS number 83799-24-0. It is the key intermediate in the synthesis of Fexofenadine Hydrochloride, a widely used second-generation antihistamine known for its non-sedative properties. SUN-VIIA plays a critical...

Fexo Base Fexofenadine (Freebase) Specifications

CAS Number

83799-24-0

Molecular Formula

C32H39NO4

Molecular Weight

538.13 g/mol

IUPAC Name

(±)-4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-butyl]-α,α-dimethyl benzeneacetic acid hydrochloride

Canonical SMILES

CC(C)(C(O)=O)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1

InChI Key

RRJFVPUCXDGFJB-UHFFFAOYSA-N

InChI

1S/C32H39NO4/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36)

UNSPSC Code

51181500

eClass

34061301

NACRES

NA.26

HSN No

3004.9

CAS Number

83799-24-0

Molecular Formula

C32H39NO4

Molecular Weight

538.13 g/mol

IUPAC Name

(±)-4-[1-Hydroxy-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-butyl]-α,α-dimethyl benzeneacetic acid hydrochloride

Canonical SMILES

CC(C)(C(O)=O)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1

InChI Key

RRJFVPUCXDGFJB-UHFFFAOYSA-N

InChI

1S/C32H39NO4/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36)

UNSPSC Code

51181500

eClass

34061301

NACRES

NA.26

HSN No

3004.9

Molecular Weight

538.13 g/mol

Melting Point

Approximately 150°C

Solubility

Slightly soluble in water; soluble in methanol and ethanol

Form

White to off-white crystalline powder

Color

White to off-white

Odor

Odorless

Shelf Life

2 years

Purity

99.50%

Hazard Statements

H302: Harmful if swallowed H315: Causes skin irritation H319: Causes serious eye irritation H332: Harmful if inhaled

Precautionary Statements

P261: Avoid breathing dust/fume/gas/mist/vapors/spray P280: Wear protective gloves/protective clothing/eye protection/face protection P304 + P340: IF INHALED: Remove person to fresh air and keep comfortable for breathing

First Aid and Emergency Measures

Inhalation: Move the person to fresh air. Seek medical attention if symptoms persist. Skin Contact: Wash affected area with soap and water. Seek medical advice if irritation persists. Eye Contact: Rinse immediately with water for at least 15 minutes. Seek medical advice if symptoms persist. Ingestion: Do not induce vomiting. Seek medical attention immediately.

GHS Classification

Acute toxicity, oral (Category 4) Skin irritation (Category 2) Eye irritation (Category 2A) Storage Class Code: 6.1B - Harmful substance, not a primary fire risk

Pharmaceuticals

Primary active pharmaceutical ingredient (API) in antihistamine formulations.

Allergy Medications

Used in the manufacture of non-sedating antihistamines, effective for treating seasonal allergic rhinitis, chronic urticaria, and other allergic reactions.